Literature DB >> 12399404

SIR2-induced inviability is suppressed by histone H4 overexpression.

Mirela Matecic1, Shelagh Stuart, Scott G Holmes.   

Abstract

We have identified histone H4 as a high-expression suppressor of Sir2-induced inviability in yeast cells. Overexpression of histone H3 does not suppress Sir2-induced lethality, nor does overexpression of histone H4 alleles associated with silencing defects. These results suggest a direct and specific interaction between Sir2 and H4 in the silencing mechanism.

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Year:  2002        PMID： 12399404      PMCID： PMC1462276     

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  21 in total

Review 1.  The Sir2 protein family: A novel deacetylase for gene silencing and more.

Authors:  D Shore
Journal:  Proc Natl Acad Sci U S A       Date:  2000-12-19       Impact factor: 11.205

2.  Sir2p exists in two nucleosome-binding complexes with distinct deacetylase activities.

Authors:  S Ghidelli; D Donze; N Dhillon; R T Kamakaka
Journal:  EMBO J       Date:  2001-08-15       Impact factor: 11.598

Review 3.  Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions.

Authors:  D D'Amours; S Desnoyers; I D'Silva; G G Poirier
Journal:  Biochem J       Date:  1999-09-01       Impact factor: 3.857

4.  Genetic analysis of histone H4: essential role of lysines subject to reversible acetylation.

Authors:  P C Megee; B A Morgan; B A Mittman; M M Smith
Journal:  Science       Date:  1990-02-16       Impact factor: 47.728

5.  The effect of gamma radiation and neocarzinostatin on NAD and ATP levels in mouse leukaemia cells.

Authors:  P M Goodwin; P J Lewis; M I Davies; C J Skidmore; S Shall
Journal:  Biochim Biophys Acta       Date:  1978-11-01

Review 6.  Enzymatic activities of Sir2 and chromatin silencing.

Authors:  D Moazed
Journal:  Curr Opin Cell Biol       Date:  2001-04       Impact factor: 8.382

7.  Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML.

Authors:  E C Park; J W Szostak
Journal:  Mol Cell Biol       Date:  1990-09       Impact factor: 4.272

8.  SRV2, a gene required for RAS activation of adenylate cyclase in yeast.

Authors:  M Fedor-Chaiken; R J Deschenes; J R Broach
Journal:  Cell       Date:  1990-04-20       Impact factor: 41.582

9.  Transcriptional silencing in yeast is associated with reduced nucleosome acetylation.

Authors:  M Braunstein; A B Rose; S G Holmes; C D Allis; J R Broach
Journal:  Genes Dev       Date:  1993-04       Impact factor: 11.361

10.  Construction of a GAL1-regulated yeast cDNA expression library and its application to the identification of genes whose overexpression causes lethality in yeast.

Authors:  H Liu; J Krizek; A Bretscher
Journal:  Genetics       Date:  1992-11       Impact factor: 4.562
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  8 in total

1.  New alleles of SIR2 define cell-cycle-specific silencing functions.

Authors:  Mirela Matecic; Kristen Martins-Taylor; Merrit Hickman; Jason Tanny; Danesh Moazed; Scott G Holmes
Journal:  Genetics       Date:  2006-06-18       Impact factor: 4.562

2.  Sirtuins as regulators of the yeast metabolic network.

Authors:  Markus Ralser; Steve Michel; Michael Breitenbach
Journal:  Front Pharmacol       Date:  2012-03-08       Impact factor: 5.810

3.  The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases.

Authors:  Andrew J Olaharski; Jasper Rine; Brett L Marshall; Joshua Babiarz; Luoping Zhang; Eric Verdin; Martyn T Smith
Journal:  PLoS Genet       Date:  2005-12-16       Impact factor: 5.917

4.  The formation of hybrid complexes between isoenzymes of glyceraldehyde-3-phosphate dehydrogenase regulates its aggregation state, the glycolytic activity and sphingolipid status in Saccharomyces cerevisiae.

Authors:  Francisca Randez-Gil; Isabel E Sánchez-Adriá; Francisco Estruch; Jose A Prieto
Journal:  Microb Biotechnol       Date:  2019-11-19       Impact factor: 5.813

5.  SIR2 Expression Noise Can Generate Heterogeneity in Viability but Does Not Affect Cell-to-Cell Epigenetic Silencing of Subtelomeric URA3 in Yeast.

Authors:  Jian Liu; Laureline Mosser; Catherine Botanch; Jean-Marie François; Jean-Pascal Capp
Journal:  G3 (Bethesda)       Date:  2020-09-02       Impact factor: 3.154

6.  Interfering with glycolysis causes Sir2-dependent hyper-recombination of Saccharomyces cerevisiae plasmids.

Authors:  Markus Ralser; Ute Zeidler; Hans Lehrach
Journal:  PLoS One       Date:  2009-04-24       Impact factor: 3.240

7.  Yeast Tdh3 (glyceraldehyde 3-phosphate dehydrogenase) is a Sir2-interacting factor that regulates transcriptional silencing and rDNA recombination.

Authors:  Alison E Ringel; Rebecca Ryznar; Hannah Picariello; Kuan-lin Huang; Asmitha G Lazarus; Scott G Holmes
Journal:  PLoS Genet       Date:  2013-10-17       Impact factor: 5.917

8.  Cytosine DNA methylation is found in Drosophila melanogaster but absent in Saccharomyces cerevisiae, Schizosaccharomyces pombe, and other yeast species.

Authors:  Floriana Capuano; Michael Mülleder; Robert Kok; Henk J Blom; Markus Ralser
Journal:  Anal Chem       Date:  2014-03-25       Impact factor: 6.986
  8 in total

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