Literature DB >> 12398758

Dissipation of the excitation wave fronts.

V N Biktashev1.   

Abstract

An excitation wave in cardiac tissue will fail to propagate if the transmembrane voltage at its front rises too slowly and does not excite the tissue ahead of it. Then the sharp voltage profile of the front will dissipate, and the subsequent spread of voltage will be purely diffusive. This mechanism is impossible in FitzHugh-Nagumo type systems. Here a simplified mathematical model for this mechanism is suggested. The model has exact traveling front solutions, and gives conditions for the front dissipation. In particular, a front will dissipate if it is not allowed to propagate faster than a certain nonzero speed. This critical speed depends only on the properties of the fast sodium current.

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Year:  2002        PMID: 12398758     DOI: 10.1103/PhysRevLett.89.168102

Source DB:  PubMed          Journal:  Phys Rev Lett        ISSN: 0031-9007            Impact factor:   9.161


  6 in total

1.  Conditions for propagation and block of excitation in an asymptotic model of atrial tissue.

Authors:  Radostin D Simitev; Vadim N Biktashev
Journal:  Biophys J       Date:  2006-01-13       Impact factor: 4.033

2.  Drift and breakup of spiral waves in reaction-diffusion-mechanics systems.

Authors:  A V Panfilov; R H Keldermann; M P Nash
Journal:  Proc Natl Acad Sci U S A       Date:  2007-04-27       Impact factor: 11.205

3.  Adapting to a changing environment: non-obvious thresholds in multi-scale systems.

Authors:  Clare Perryman; Sebastian Wieczorek
Journal:  Proc Math Phys Eng Sci       Date:  2014-10-08       Impact factor: 2.704

4.  Dispersion of cardiac action potential duration and the initiation of re-entry: a computational study.

Authors:  Richard H Clayton; Arun V Holden
Journal:  Biomed Eng Online       Date:  2005-02-18       Impact factor: 2.819

5.  BeatBox-HPC simulation environment for biophysically and anatomically realistic cardiac electrophysiology.

Authors:  Mario Antonioletti; Vadim N Biktashev; Adrian Jackson; Sanjay R Kharche; Tomas Stary; Irina V Biktasheva
Journal:  PLoS One       Date:  2017-05-03       Impact factor: 3.240

6.  A Simulation Study of the Role of Mechanical Stretch in Arrhythmogenesis during Cardiac Alternans.

Authors:  Azzam Hazim; Youssef Belhamadia; Stevan Dubljevic
Journal:  Biophys J       Date:  2020-11-26       Impact factor: 4.033

  6 in total

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