| Literature DB >> 12398517 |
Mandy K S Vink1, Christien A Schortinghuis, Jordy Luten, Jan H Van Maarseveen, Hans E Schoemaker, Henk Hiemstra, Floris P J T Rutjes.
Abstract
A stereodivergent route toward both diastereomeric forms of functionalized 4-hydroxypiperidines has been successfully developed. This route involves biocatalytic generation of the enantiopure starting materials followed by functionalization via N-acyliminium ion-mediated CC-bond formation.Entities:
Year: 2002 PMID： 12398517 DOI： 10.1021/jo025943o
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354