Literature DB >> 1239827

Evans blue: a specific inhibitor of factor VIII-induced platelet agglutination.

E P Kirby.   

Abstract

Low concentrations of Evans Blue (less than 1 muM) inhibit the agglutination of formalin-treated platelets by bovine Factor VIII or by human Factor VIII in the presence of the antibiotic ristocetin. Evans Blue is a specific inhibitor of this reaction and acts by inhibiting the binding of Factor VIII to the platelet surface.

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Year:  1975        PMID： 1239827

Source DB:  PubMed          Journal:  Thromb Diath Haemorrh        ISSN： 0340-5338


  3 in total

1.  The effects of ristocetin and von Willebrand factor on platelet electrophoretic mobility.

Authors:  B S Coller
Journal:  J Clin Invest       Date:  1978-05       Impact factor: 14.808

2.  Studies on the mechanism of ristocetin-induced platelet agglutination. Effects of structural modification of ristocetin and vancomycin.

Authors:  B S Coller; H R Gralnick
Journal:  J Clin Invest       Date:  1977-08       Impact factor: 14.808

3.  Platelet receptors for human Factor VIII/von Willebrand protein: functional correlation of receptor occupancy and ristocetin-induced platelet aggregation.

Authors:  K J Kao; S V Pizzo; P A McKee
Journal:  Proc Natl Acad Sci U S A       Date:  1979-10       Impact factor: 11.205
  3 in total

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