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Literature DB >> 12398117

Gene therapy--its potential in surgery.

Satoshi Gojo, Shin Yamamoto, Clive Patience, Christian LeGuern, David K C Cooper.

Abstract

Advances in techniques have resulted in practical applications for gene therapy, which is becoming applicable for the treatment of human disease. This review outlines the advantages and disadvantages of the techniques available. Examples of research efforts in the treatment of diseases of relevance to the surgeon (cardiovascular diseases, cancer, wound healing, fracture repair, and in organ transplantation) are presented.

Entities: Disease Species

Mesh：

Year: 2002 PMID： 12398117 PMCID： PMC2504171 DOI： 10.1308/003588402760452367

Source DB: PubMed Journal: Ann R Coll Surg Engl ISSN： 0035-8843 Impact factor: 1.891

20 in total

1. Gene-enhanced tissue engineering: applications for wound healing using cultured dermal fibroblasts transduced retrovirally with the PDGF-B gene.

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Journal: Ann Plast Surg Date: 1999-12 Impact factor: 1.539

2. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

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Journal: Proc Natl Acad Sci U S A Date: 1987-11 Impact factor: 11.205

3. Genetic enhancement of fracture repair: healing of an experimental segmental defect by adenoviral transfer of the BMP-2 gene.

Authors: A W Baltzer; C Lattermann; J D Whalen; P Wooley; K Weiss; M Grimm; S C Ghivizzani; P D Robbins; C H Evans
Journal: Gene Ther Date: 2000-05 Impact factor: 5.250

4. Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial.

Authors: A K Stewart; N J Lassam; I C Quirt; D J Bailey; L E Rotstein; M Krajden; S Dessureault; S Gallinger; D Cappe; Y Wan; C L Addison; R C Moen; J Gauldie; F L Graham
Journal: Gene Ther Date: 1999-03 Impact factor: 5.250

5. Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: the PREVENT single-centre, randomised, controlled trial.

Authors: M J Mann; A D Whittemore; M C Donaldson; M Belkin; M S Conte; J F Polak; E J Orav; A Ehsan; G Dell'Acqua; V J Dzau
Journal: Lancet Date: 1999-10-30 Impact factor: 79.321

Review 6. Gene therapy and transplantation.

Authors: S Gojo; D K Cooper; J Iacomini; C LeGuern
Journal: Transplantation Date: 2000-05-27 Impact factor: 4.939

7. Adenoviral-mediated overexpression of platelet-derived growth factor-B corrects ischemic impaired wound healing.

Authors: K W Liechty; M Nesbit; M Herlyn; A Radu; N S Adzick; T M Crombleholme
Journal: J Invest Dermatol Date: 1999-09 Impact factor: 8.551

8. Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report.

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Journal: N Engl J Med Date: 1988-12-22 Impact factor: 91.245

9. Prospects for human gene therapy.

Authors: W F Anderson
Journal: Science Date: 1984-10-26 Impact factor: 47.728

10. Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence.

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Journal: Cancer Res Date: 1996-01-15 Impact factor: 12.701

4 in total

Review 1. [Plastic surgery of skin defects in the face. Principles and perspectives].

Authors: F Riedel; K Hörmann
Journal: HNO Date: 2005-12 Impact factor: 1.284

Review 2. [Regenerative medicine in head and neck reconstructive surgery].

Authors: F Riedel; U R Goessler; J Stern-Straeter; K Riedel; K Hörmann
Journal: HNO Date: 2008-03 Impact factor: 1.284

3. Interleukin-10 modified dendritic cells induce allo-hyporesponsiveness and prolong small intestine allograft survival.

Authors: Min Zhu; Ming-Fa Wei; Fang Liu; Hui-Fen Shi; Guo Wang
Journal: World J Gastroenterol Date: 2003-11 Impact factor: 5.742

Review 4. [Pathogenesis of chronic wounds].

Authors: K Riedel; H Ryssel; E Koellensperger; G Germann; T Kremer
Journal: Chirurg Date: 2008-06 Impact factor: 0.920

4 in total