Literature DB >> 12397997

Quantitative determination of the enantiomeric composition of thalidomide solutions by electrospray ionization tandem mass spectrometry.

Daniella V Augusti1, Rodinei Augusti, Fernando Carazza, R Graham Cooks.   

Abstract

Rapid and simple chiral analysis of thalidomide solutions is demonstrated by using electrospray ionization tandem mass spectrometry and analysis of cluster ion dissociation by the kinetic method. Average deviations of 1% between the actual and experimental enantiomeric compositions are observed.

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Year:  2002        PMID： 12397997     DOI： 10.1039/b204421h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Direct quantitation of peptide mixtures without standards using clusters formed by electrospray ionization mass spectrometry.

Authors:  Ryan D Leib; Tawnya G Flick; Evan R Williams
Journal:  Anal Chem       Date:  2009-05-15       Impact factor: 6.986

2.  Stereoselectivity in the collision-activated reactions of gas phase salt complexes.

Authors:  Scott Gronert; Adelaide E Fagin; Keiko Okamoto
Journal:  J Am Soc Mass Spectrom       Date:  2004-10       Impact factor: 3.109

3.  Chiral Differentiation of Amino Acids by In-Source Collision-Induced Dissociation Mass Spectrometry.

Authors:  Xianglei Kong; Zhaiyi Huo; Wei Zhai
Journal:  Mass Spectrom (Tokyo)       Date:  2014-05-01
  3 in total

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