Literature DB >> 12396942

[At what care level are cyclo-oxygenase-2 inhibitors prescribed?].

M J Montero Fernández1, F J Rodríguez Alcalá, N Valles Fernández, F López de Castro, M Esteban Tudela, B Cordero García.   

Abstract

OBJECTIVES: To find the evolution in the billing of prescriptions for selective cyclooxygenase-2 (COX-2) inhibitors since they came on the market and to compare this evolution in primary care (PC) and specialist care (SC).Design. Cross-sectional, descriptive study.
SETTING: Toledo Health Area. Main measurements. Data were obtained from the System of Drug Information (SIFAR) to analyse the monthly turnover of NSAID prescriptions (M01A group in the official classification of medicines, including rofecoxib and celecoxib) issued by doctors in PC and SC between January 2000 and June 2001.
RESULTS: In our area during the study period, 583,558 NSAID packages were prescribed; 6.61% were COX-2 inhibitors, which represented 29.08% of NSAID expenditure. 98.23% of NSAID packages and 94.61% of COX-2 inhibitors were prescribed in PC. The use of COX-2 inhibitors in SC rose from 10.03% of the total NSAIDs in February 2000 to 29.79% in June 2001; whilst in PC it rose from 1.52% to 10.78%. Rofecoxib and celecoxib were third and fifth in the lists of most prescribed NSAIDs (number of packages) in SC, and ninth and twelfth in PC. In terms of cost of prescription, they were first and second in SC, and first and fourth in PC.
CONCLUSIONS: COX-2 inhibitors have become the main NSAIDs prescribed. The appearance of these drugs had a different impact on SC and PC doctors, with greater use of them and a more rapid introduction in SC.

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Year:  2002        PMID: 12396942      PMCID: PMC7676627          DOI: 10.1016/s0212-6567(02)79048-3

Source DB:  PubMed          Journal:  Aten Primaria        ISSN: 0212-6567            Impact factor:   1.137


  19 in total

1.  [Prescription use by specialist care in the Toledo Health Area].

Authors:  B Viñas González; R López Serrano; M J Montero Fernández; B Cordero García; M Esteban Tudela; F López de Castro
Journal:  Aten Primaria       Date:  1999-04-15       Impact factor: 1.137

2.  [Pharmaceutic promotion and publicity: quo vadis?].

Authors:  P Castillo Pérez
Journal:  Med Clin (Barc)       Date:  1992-09-19       Impact factor: 1.725

3.  [Epidemiology and the pharmaceutical industry].

Authors:  A M Walker; L A García Rodríguez; S Pérez Gutthann
Journal:  Med Clin (Barc)       Date:  1992-03-28       Impact factor: 1.725

Review 4.  [Factors affecting drug prescriptions by the primary care physician].

Authors:  J C Abánades Herranz; V Cabedo García; R Cunillera Grañó; J J Garcia Díez; L Jolín Garijo; M Martín Bun; S Prados Torres; C Vicens Caldentey
Journal:  Aten Primaria       Date:  1998-10-15       Impact factor: 1.137

5.  [Induced prescription: excuse or reality?].

Authors:  J A García Vicente; F Cordón Granados
Journal:  Aten Primaria       Date:  1998-12       Impact factor: 1.137

6.  [Pharmaceutical expenditure in primary care according to the prescription source].

Authors:  J A Lomeña Villalobos; M Ceballos Vacas; M T Medina Arteaga; E Mediavilla Cordero; F Sarmiento Jiménez; J L Hernández Grande
Journal:  Aten Primaria       Date:  1996-06-15       Impact factor: 1.137

7.  [Can we decrease pharmacy costs?].

Authors:  R Azagra Ledesma
Journal:  Aten Primaria       Date:  1993-02-28       Impact factor: 1.137

8.  Modelling the market uptake of new drugs following listing for subsidy in Australia. A report from the Drug Utilisation Subcommittee of the Australian Pharmaceutical Benefits Advisory Committee.

Authors:  D J Birkett; P McManus
Journal:  Br J Clin Pharmacol       Date:  1995-10       Impact factor: 4.335

9.  Hospital initiated prescribing in the General Medical Services scheme.

Authors:  T Fahey; H Sinclair
Journal:  Ir Med J       Date:  1993 Jul-Aug

Review 10.  COX-2 selective nonsteroidal anti-Inflammatory drugs: do they really offer any advantages?

Authors:  L M Jackson; C J Hawkey
Journal:  Drugs       Date:  2000-06       Impact factor: 9.546

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