| Literature DB >> 12396379 |
P M Satturwar1, P M Mandaogade, A K Dorle.
Abstract
A novel technique for the preparation of Eudragit RL microcapsules is described. The technique is based on the principle of solvent evaporation. Diclofenac sodium is used as a model drug for encapsulation. A solution of drug and Eudragit RL dissolved in acetone-isopropyl alcohol (1:1) is sprayed in liquid paraffin. The microcapsules obtained were uniform and free flowing particles. The release rate was more sustained by increasing the polymer concentration. The experimental procedure promises a rapid and convenient method for the preparation of Eudragit RL-microcapsules.Entities:
Mesh：
Substances：
Year: 2002 PMID： 12396379 DOI： 10.1080/02652040210140454
Source DB: PubMed Journal: J Microencapsul ISSN： 0265-2048 Impact factor: 3.142