Literature DB >> 12394966

A review of nerve agent exposure for the critical care physician.

Jerrold B Leikin1, Richard G Thomas, Frank G Walter, Raymond Klein, Harvey W Meislin.   

Abstract

Nerve agents are discussed. The article discusses their properties, routes of exposure, toxicodynamics, targets of toxicity, and treatment. It is concluded that a focused organized approach to the treatment of nerve agents is key to its successful management.

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Year:  2002        PMID: 12394966     DOI: 10.1097/00003246-200210000-00026

Source DB:  PubMed          Journal:  Crit Care Med        ISSN: 0090-3493            Impact factor:   7.598


  14 in total

1.  Spatiotemporal pattern of neuronal injury induced by DFP in rats: a model for delayed neuronal cell death following acute OP intoxication.

Authors:  Yonggang Li; Pamela J Lein; Cuimei Liu; Donald A Bruun; Teclemichael Tewolde; Gregory Ford; Byron D Ford
Journal:  Toxicol Appl Pharmacol       Date:  2011-04-12       Impact factor: 4.219

Review 2.  Organophosphorus pesticide determination in biological specimens: bioanalytical and toxicological aspects.

Authors:  Sofia Soares; Tiago Rosado; Mário Barroso; Duarte Nuno Vieira; Eugenia Gallardo
Journal:  Int J Legal Med       Date:  2019-07-12       Impact factor: 2.686

3.  Midazolam-Resistant Seizures and Brain Injury after Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents.

Authors:  Xin Wu; Ramkumar Kuruba; Doodipala Samba Reddy
Journal:  J Pharmacol Exp Ther       Date:  2018-08-16       Impact factor: 4.030

Review 4.  Sarin (GB, O-isopropyl methylphosphonofluoridate) neurotoxicity: critical review.

Authors:  Mohamed B Abou-Donia; Briana Siracuse; Natasha Gupta; Ashly Sobel Sokol
Journal:  Crit Rev Toxicol       Date:  2016-10-05       Impact factor: 5.635

5.  Nerve Agent Incidents and Public Health Preparedness.

Authors:  Arthur Chang; Jerry Thomas; Rudolph Johnson; Susan E Gorman; Josh Schier; Luke Yip
Journal:  Ann Intern Med       Date:  2018-12-18       Impact factor: 25.391

6.  Engineering Dynamic Surface Peptide Networks on ButyrylcholinesteraseG117H for Enhanced Organophosphosphorus Anticholinesterase Catalysis.

Authors:  Kirstin P Hester; Krishna Bhattarai; Haobo Jiang; Pratul K Agarwal; Carey Pope
Journal:  Chem Res Toxicol       Date:  2019-08-28       Impact factor: 3.739

Review 7.  Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents.

Authors:  Isaac N Pessah; Michael A Rogawski; Daniel J Tancredi; Heike Wulff; Dorota Zolkowska; Donald A Bruun; Bruce D Hammock; Pamela J Lein
Journal:  Ann N Y Acad Sci       Date:  2016-07-28       Impact factor: 5.691

Review 8.  Enhancing organophosphate hydrolase efficacy via protein engineering and immobilization strategies.

Authors:  Priya Katyal; Stanley Chu; Jin Kim Montclare
Journal:  Ann N Y Acad Sci       Date:  2020-08-19       Impact factor: 5.691

9.  Enzymatic neutralization of the chemical warfare agent VX: evolution of phosphotriesterase for phosphorothiolate hydrolysis.

Authors:  Andrew N Bigley; Chengfu Xu; Terry J Henderson; Steven P Harvey; Frank M Raushel
Journal:  J Am Chem Soc       Date:  2013-07-09       Impact factor: 15.419

10.  Advances in toxicology and medical treatment of chemical warfare nerve agents.

Authors:  Mohammd Moshiri; Emadodin Darchini-Maragheh; Mahdi Balali-Mood
Journal:  Daru       Date:  2012-11-28       Impact factor: 3.117

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