Literature DB >> 12393840

Does loss of bile acid homeostasis make mice melancholy?

David D Moore1.   

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Year:  2002        PMID： 12393840      PMCID： PMC150805          DOI： 10.1172/JCI16943

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


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  14 in total

1.  Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway.

Authors:  S Gupta; R T Stravitz; P Dent; P B Hylemon
Journal:  J Biol Chem       Date:  2001-02-13       Impact factor: 5.157

2.  Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner.

Authors:  Yoon-Kwang Lee; David D Moore
Journal:  J Biol Chem       Date:  2001-10-19       Impact factor: 5.157

3.  An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

Authors:  W Xie; A Radominska-Pandya; Y Shi; C M Simon; M C Nelson; E S Ong; D J Waxman; R M Evans
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-13       Impact factor: 11.205

4.  The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity.

Authors:  J L Staudinger; B Goodwin; S A Jones; D Hawkins-Brown; K I MacKenzie; A LaTour; Y Liu; C D Klaassen; K K Brown; J Reinhard; T M Willson; B H Koller; S A Kliewer
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-13       Impact factor: 11.205

5.  Vitamin D receptor as an intestinal bile acid sensor.

Authors:  Makoto Makishima; Timothy T Lu; Wen Xie; G Kerr Whitfield; Hideharu Domoto; Ronald M Evans; Mark R Haussler; David J Mangelsdorf
Journal:  Science       Date:  2002-05-17       Impact factor: 47.728

6.  Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

Authors:  C J Sinal; M Tohkin; M Miyata; J M Ward; G Lambert; F J Gonzalez
Journal:  Cell       Date:  2000-09-15       Impact factor: 41.582

7.  A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis.

Authors:  B Goodwin; S A Jones; R R Price; M A Watson; D D McKee; L B Moore; C Galardi; J G Wilson; M C Lewis; M E Roth; P R Maloney; T M Willson; S A Kliewer
Journal:  Mol Cell       Date:  2000-09       Impact factor: 17.970

8.  Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors.

Authors:  T T Lu; M Makishima; J J Repa; K Schoonjans; T A Kerr; J Auwerx; D J Mangelsdorf
Journal:  Mol Cell       Date:  2000-09       Impact factor: 17.970

9.  Cholic acid mediates negative feedback regulation of bile acid synthesis in mice.

Authors:  Jia Li-Hawkins; Mats Gåfvels; Maria Olin; Erik G Lund; Ulla Andersson; Gertrud Schuster; Ingemar Björkhem; David W Russell; Gosta Eggertsen
Journal:  J Clin Invest       Date:  2002-10       Impact factor: 14.808

10.  Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis.

Authors:  Thomas A Kerr; Shigeru Saeki; Manfred Schneider; Karen Schaefer; Sara Berdy; Thadd Redder; Bei Shan; David W Russell; Margrit Schwarz
Journal:  Dev Cell       Date:  2002-06       Impact factor: 12.270
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  2 in total

1.  Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes.

Authors:  Ji Miao; Sung-E Choi; Sun Mi Seok; Linda Yang; William J Zuercher; Yong Xu; Timothy M Willson; H Eric Xu; Jongsook Kim Kemper
Journal:  Mol Endocrinol       Date:  2011-05-12

2.  Genetic ablation of Cyp8b1 preserves host metabolic function by repressing steatohepatitis and altering gut microbiota composition.

Authors:  Jay V Patankar; Chi K Wong; Vijay Morampudi; William T Gibson; Bruce Vallance; George N Ioannou; Michael R Hayden
Journal:  Am J Physiol Endocrinol Metab       Date:  2017-10-24       Impact factor: 4.310
  2 in total

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