Literature DB >> 1239331

The effect of isoprenaline and propranolol on rat myocardial ornithine decarboxylase.

J W Warnica, P Antony, K Gibson, P Harris.   

Abstract

The intraperitoneal injection of isoprenaline in rats caused an increase in myocardial ornithine decarboxylase activity which reached a maximum of about four times the control value one hour after the injection. The intraperitoneal injection of dl-propranolol had no effect on myocardial ornithine decarboxylase activity. The injection of dl-propranolol 30 min before the injection of isoprenaline almost completely prevented the effect of isoprenaline.

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Year:  1975        PMID： 1239331     DOI： 10.1093/cvr/9.6.793

Source DB:  PubMed          Journal:  Cardiovasc Res        ISSN： 0008-6363            Impact factor:   10.787


  4 in total

1.  Accumulation of N1-acetylspermidine in heart and spleen of isoprenaline-treated rats.

Authors:  C Stefanelli; D Carati; C Rossoni; F Flamigni; C M Caldarera
Journal:  Biochem J       Date:  1986-08-01       Impact factor: 3.857

2.  Overexpression of antizyme in the hearts of transgenic mice prevents the isoprenaline-induced increase in cardiac ornithine decarboxylase activity and polyamines, but does not prevent cardiac hypertrophy.

Authors:  C A Mackintosh; D J Feith; L M Shantz; A E Pegg
Journal:  Biochem J       Date:  2000-09-15       Impact factor: 3.857

3.  beta 2-Adrenoceptors regulate induction of myocardial ornithine decarboxylase in mice in vivo.

Authors:  J G Copeland; D F Larson; W R Roeske; D H Russell; J R Womble
Journal:  Br J Pharmacol       Date:  1982-03       Impact factor: 8.739

4.  Involvement of calcium ions in the activation of ornithine decarboxylase by isoprenaline evaluated 'in situ' in the perfused rat heart.

Authors:  C Guarnieri; F Flamigni; C Muscari; C M Caldarera
Journal:  Biochem J       Date:  1983-04-15       Impact factor: 3.857
  4 in total

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