Literature DB >> 12392337

Cervical myelopathy and rheumatoid arthritis: a retrospective analysis of management.

Z F Falope1, I D Griffiths, P N Platt, N V Todd.   

Abstract

BACKGROUND: Although a number of recent studies have described the outcome of surgical treatment of patients with rheumatoid cervical myelopathy, few have reported outcome in those unable to have surgery. We sought to examine the outcome in this group of patients regardless of surgical intervention.
DESIGN: Retrospective and descriptive.
SETTING: Department of Rheumatology, Freeman Hospital, Newcastle upon Tyne, UK.
METHODS: Retrospective review of case notes of 40 patients (31 females, 9 males) with rheumatoid cervical myelopathy diagnosed 1988-1997.
RESULTS: The mean age was 64 years (range 36-80 years). The mean duration of rheumatoid arthritis (RA) before the development of myelopathy was 21 years (range 5-44 years). The common impairments were paraesthesia in the arms, neck pain and weakness. Twenty-five patients (60%) were deemed fit for surgery (group I). Twenty-two patients successfully had operative treatment and the others refused. Twelve of the 15 patients who reported pain preoperatively obtained pain relief. Six of the 11 patients who were nonambulant (Ranawat class IIIB) were able to walk postoperatively. There were two deaths within six months (9% mortality) after primary surgery due to pneumonia and sepsis. Seven of the 15 patients managed conservatively (group II) because of coexisting medical complications died within six months of presentation (47% mortality).
CONCLUSIONS: The study confirms the overall benefit of surgical intervention in those who are medically stable. Following surgery some functional improvement may occur even in patients with severe myelopathy.

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Year:  2002        PMID: 12392337     DOI: 10.1191/0269215502cr531oa

Source DB:  PubMed          Journal:  Clin Rehabil        ISSN: 0269-2155            Impact factor:   3.477


  5 in total

Review 1.  [Instability of the upper cervical spine due to rheumatism].

Authors:  C E Heyde; U Weber; R Kayser
Journal:  Orthopade       Date:  2006-03       Impact factor: 1.087

Review 2.  Cervical spine instability in rheumatoid arthritis.

Authors:  Filipa Camacho da Côrte; Nuno Neves
Journal:  Eur J Orthop Surg Traumatol       Date:  2013-06-27

Review 3.  [Cervical myelopathy as a complication of rheumatoid arthritis].

Authors:  A C Arlt; J Steinmetz
Journal:  Z Rheumatol       Date:  2004-08       Impact factor: 1.372

4.  Cervical myelopathy in rheumatoid arthritis.

Authors:  N Mukerji; N V Todd
Journal:  Neurol Res Int       Date:  2011-11-22

5.  Rationale and design of The Delphi Trial--I(RCT)2: international randomized clinical trial of rheumatoid craniocervical treatment, an intervention-prognostic trial comparing 'early' surgery with conservative treatment [ISRCTN65076841].

Authors:  Jasper F C Wolfs; Wilco C Peul; Maarten Boers; Maurits W van Tulder; Ronald Brand; Hans J C van Houwelingen; Raph T W M Thomeer
Journal:  BMC Musculoskelet Disord       Date:  2006-02-16       Impact factor: 2.362

  5 in total

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