Literature DB >> 12390852

[Serum uric acid in type 2 diabetic patients complicated by stroke].

Mei-Ping Guan1, Yao-Ming Xue, Jie Shen, Lin Zhou, Fang Gao, Shi-Qun Liu, Chen-Zhong Li.   

Abstract

OBJECTIVE: To investigate the association of hyperuricemia with the incidence of stroke in type 2 diabetic patients.
METHODS: Sixty type 2 diabetic patients with stroke, 75 patients with simple stoke and 67 simple type 2 diabetic patients were randomly selected from the hospitalized patients. The serum levels of uric acid (UA), total cholesterol (TC), triglyceride (TG), low-density lipoprotein-cholesterol(LDL), very-low-density lipoproteincholesterol (VLDL) and high-density lipoprotein- cholesterol (HDL) of all the patients were determined and comparison between the groups performed.
RESULTS: Male type 2 diabetic patients with stroke had significantly higher mean levels of serum uric acid than simple diabetic patients, but such patients of both genders all had lower HDL levels.
CONCLUSION: The decreased serum HDL level poses as an important risk factor for stroke in all type 2 diabetic patients, among whom the male patients in particular have hyperuricemia as another important risk factor for stroke.

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Year:  2002        PMID: 12390852

Source DB:  PubMed          Journal:  Di Yi Jun Yi Da Xue Xue Bao        ISSN: 1000-2588


  2 in total

Review 1.  Higher Serum Uric Acid May Contribute to Cerebral Infarction in Patients with Type 2 Diabetes Mellitus: a Meta-Analysis.

Authors:  Lei Du; Jianhua Ma; Xiaoning Zhang
Journal:  J Mol Neurosci       Date:  2016-10-01       Impact factor: 3.444

2.  Acute ischemic non-embolic stroke and serum level of uric acid.

Authors:  Farhad Iranmanesh; Nazanin Zia Sheykholeslami; Faranak Gadari; Jafar Ahmady
Journal:  Iran J Neurol       Date:  2012
  2 in total

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