Literature DB >> 12390044

Treatment of childhood eczema.

Håkan Granlund1.   

Abstract

Eczema in childhood is almost always atopic eczema, a common disease with huge impact on the quality of life of the child and family. Although atopic eczema constitutes part of the atopic syndrome, avoidance of allergens is never enough for disease control. Treatment of eczema in childhood has the same components as in adults. Emollients constitute the preventive background therapy in all stages of eczema, and topical corticosteroids are still the mainstay of treatment. Infectious exacerbation may require the use of a short course of topical or systemic antimicrobials. UV phototherapy should be considered as an adjunctive treatment to assist topical corticosteroids after an acute exacerbation of the disease. Cyclosporine can also be used in the treatment of childhood eczema in severe cases. Maternal allergen avoidance for disease prevention, oral antihistamines, Chinese herbs, dietary restriction in established atopic eczema, homeopathy, house-dust mite reduction, massage therapy, hypnotherapy, evening primrose oil, emollients, and topical coal tar are other temporarily used treatment modalities, without, however, firm evidence of efficacy from proper controlled trials. Calcineurin inhibitors constitute a new generation of drugs for both adult and childhood eczema already marketed in some countries. It is postulated that they will replace topical corticosteroids as first-line treatment of eczema.

Entities:  

Mesh:

Substances:

Year:  2002        PMID: 12390044     DOI: 10.2165/00128072-200204110-00004

Source DB:  PubMed          Journal:  Paediatr Drugs        ISSN: 1174-5878            Impact factor:   3.022


  63 in total

1.  Effect of house dust mite avoidance measures in children with atopic dermatitis.

Authors:  R A Palmer; P S Friedmann
Journal:  Br J Dermatol       Date:  2001-04       Impact factor: 9.302

2.  Moisturizers prevent irritant dermatitis.

Authors:  A Hannuksela; T Kinnunen
Journal:  Acta Derm Venereol       Date:  1992       Impact factor: 4.437

3.  A controlled trial of traditional Chinese herbal medicine in Chinese patients with recalcitrant atopic dermatitis.

Authors:  A Y Fung; P C Look; L Y Chong; P P But; E Wong
Journal:  Int J Dermatol       Date:  1999-05       Impact factor: 2.736

Review 4.  Breast-feeding and the onset of atopic dermatitis in childhood: a systematic review and meta-analysis of prospective studies.

Authors:  M Gdalevich; D Mimouni; M David; M Mimouni
Journal:  J Am Acad Dermatol       Date:  2001-10       Impact factor: 11.527

5.  Long-term follow-up of eczema patients treated with cyclosporine.

Authors:  H Granlund; P Erkko; S Reitamo
Journal:  Acta Derm Venereol       Date:  1998-01       Impact factor: 4.437

6.  Prophylaxis of atopic disease by six months' total solid food elimination. Evaluation of 135 exclusively breast-fed infants of atopic families.

Authors:  M Kajosaari; U M Saarinen
Journal:  Acta Paediatr Scand       Date:  1983-05

7.  Thymopentin treatment in severe atopic dermatitis--clinical and immunological evaluations.

Authors:  K H Hsieh; M F Shaio; T N Liao
Journal:  Arch Dis Child       Date:  1992-09       Impact factor: 3.791

8.  Therapy of infected dermatitis: comparative response to two corticosteroid antimicrobial creams.

Authors:  R D Wilkinson; J P Collins; G P Raymond; R Mailhot; M A Perras; P Ricard
Journal:  J Am Acad Dermatol       Date:  1980-03       Impact factor: 11.527

9.  Multicenter trial for long-term safety and efficacy comparison of 0.05% desonide and 1% hydrocortisone ointments in the treatment of atopic dermatitis in pediatric patients.

Authors:  J Jorizzo; M Levy; A Lucky; J Shavin; G Goldberg; F Dunlap; A Hinds; L Strelka; M Baker; M Tuley
Journal:  J Am Acad Dermatol       Date:  1995-07       Impact factor: 11.527

10.  Effect of n-3 fatty acid supplement to patients with atopic dermatitis.

Authors:  A Bjørneboe; E Søyland; G E Bjørneboe; G Rajka; C A Drevon
Journal:  J Intern Med Suppl       Date:  1989
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.