Myriam A J Mondestin1, Cande V Ananth, John C Smulian, Anthony M Vintzileos. 1. Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School/Saint Peter's University Hospital, New Brunswick, NJ, USA.
Abstract
OBJECTIVE: Our purpose was to evaluate the association between birth weight (BW) and fetal death (FD) among pregnant nondiabetic and diabetic patients. STUDY DESIGN: This was a retrospective cohort study using data for singleton births delivered between 1995 and 1997 in the United States (n = 10, 733, 983). Analysis was restricted to births that occurred at > or =20 completed weeks. FD rates among nondiabetic and diabetic patients (n = 271, 691) were determined for different 250-g BW categories. Adjusted relative risk (RR) and 95% CI for FD among diabetic compared with nondiabetic patients were derived through multivariable logistic regression models after potential confounders were controlled. RESULTS: Overall FD rates for nondiabetic and diabetic patients were 4.0 and 5.9 per 1,000 births, respectively, with adjusted RR of 2.0 (95% CI 1.8-2.2). Maternal diabetes was associated with increased FD rate for all BW categories after 1250 g. CONCLUSION: The FD rate is increased when birth weight is > or =4250 g in nondiabetic patients and > or =4000 g in diabetic patients.
OBJECTIVE: Our purpose was to evaluate the association between birth weight (BW) and fetal death (FD) among pregnant nondiabetic and diabeticpatients. STUDY DESIGN: This was a retrospective cohort study using data for singleton births delivered between 1995 and 1997 in the United States (n = 10, 733, 983). Analysis was restricted to births that occurred at > or =20 completed weeks. FD rates among nondiabetic and diabeticpatients (n = 271, 691) were determined for different 250-g BW categories. Adjusted relative risk (RR) and 95% CI for FD among diabetic compared with nondiabetic patients were derived through multivariable logistic regression models after potential confounders were controlled. RESULTS: Overall FD rates for nondiabetic and diabeticpatients were 4.0 and 5.9 per 1,000 births, respectively, with adjusted RR of 2.0 (95% CI 1.8-2.2). Maternal diabetes was associated with increased FD rate for all BW categories after 1250 g. CONCLUSION: The FD rate is increased when birth weight is > or =4250 g in nondiabetic patients and > or =4000 g in diabeticpatients.
Authors: Katarzyna Cyganek; Alicja Hebda-Szydlo; Jan Skupien; Barbara Katra; Izabela Janas; Alicja Borodako; Irena Kaim; Tomasz Klupa; Alfred Reron; Maciej T Malecki Journal: Endocrine Date: 2011-04-29 Impact factor: 3.633
Authors: Peter W G Tennant; Svetlana V Glinianaia; Rudy W Bilous; Judith Rankin; Ruth Bell Journal: Diabetologia Date: 2013-11-29 Impact factor: 10.122