Literature DB >> 12388815

Excretion of herpes simplex virus type 2 glycoprotein D into the culture medium.

Takayuki Murata1, Fumi Goshima1, Hiroki Takakuwa1, Yukihiro Nishiyama1.   

Abstract

Glycoprotein D (gD) of herpes simplex virus type 2 (HSV-2) was excreted from infected cells into the medium. Peptide mapping analysis and lectin binding assays suggested that the gD in the medium is secreted after full glycosylation and cleavage at its C terminus. Release of HSV-2 gD was inhibited by addition of either tunicamycin or brefeldin A, suggesting that the gD in the medium was secreted through the endoplasmic reticulum and Golgi apparatus.

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Year:  2002        PMID： 12388815     DOI： 10.1099/0022-1317-83-11-2791

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  3 in total

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Authors:  Maaike E Ressing; Daphne van Leeuwen; Frank A W Verreck; Sinéad Keating; Raquel Gomez; Kees L M C Franken; Tom H M Ottenhoff; Melanie Spriggs; Ton N Schumacher; Lindsey M Hutt-Fletcher; Martin Rowe; Emmanuel J H J Wiertz
Journal:  J Virol       Date:  2005-01       Impact factor: 5.103

2.  Envelope protein requirements for the assembly of infectious virions of porcine reproductive and respiratory syndrome virus.

Authors:  E H J Wissink; M V Kroese; H A R van Wijk; F A M Rijsewijk; J J M Meulenberg; P J M Rottier
Journal:  J Virol       Date:  2005-10       Impact factor: 5.103

3.  Topical herpes simplex virus 2 (HSV-2) vaccination with human papillomavirus vectors expressing gB/gD ectodomains induces genital-tissue-resident memory CD8+ T cells and reduces genital disease and viral shedding after HSV-2 challenge.

Authors:  Nicolas Çuburu; Kening Wang; Kyle N Goodman; Yuk Ying Pang; Cynthia D Thompson; Douglas R Lowy; Jeffrey I Cohen; John T Schiller
Journal:  J Virol       Date:  2014-10-15       Impact factor: 5.103
  3 in total

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