Literature DB >> 12386367

Histologic appearance of endometriosis infiltrating uterosacral ligaments in women with painful symptoms.

Hélène Bonte1, Charles Chapron, Marco Vieira, Arnaud Fauconnier, Habib Barakat, Xavier Fritel, Marie-Cécile Vacher-Lavenu, Jean-Bernard Dubuisson.   

Abstract

STUDY
OBJECTIVE: To describe the histologic appearance of deep endometriosis infiltrating the uterosacral ligaments (USL).
DESIGN: Retrospective analysis (Canadian Task Force classification II-2).
SETTING: University-affiliated hospital. PATIENTS: One hundred forty-nine women with pain due to endometriosis. INTERVENTION: Resection of one or both USL.
MEASUREMENTS AND MAIN RESULTS: One hundred seventy-two USL were examined by histology after unilateral resection in 126 patients (84.6%) and bilateral resection in 23 (15.4%). Two-thirds of women (122, 70.9%) had a classic appearance of endometriosis. Lesions of myoproliferative endometriosis with a histologic appearance of so-called adenomyotic nodules were observed in 25 (14.5%). Associated fibrosis was most frequent in patients with positive compared with negative histology (85, 69.7% vs 18, 36.0%).
CONCLUSION: Anatomicopathologic lesions of deep endometriosis infiltrating the USL are heterogeneous. Adenomyotic nodules are not frequently observed.

Entities:  

Mesh:

Year:  2002        PMID: 12386367     DOI: 10.1016/s1074-3804(05)60530-0

Source DB:  PubMed          Journal:  J Am Assoc Gynecol Laparosc        ISSN: 1074-3804


  4 in total

1.  Antiproliferative effects of cannabinoid agonists on deep infiltrating endometriosis.

Authors:  Mahaut Leconte; Carole Nicco; Charlotte Ngô; Sylviane Arkwright; Christiane Chéreau; Jean Guibourdenche; Bernard Weill; Charles Chapron; Bertrand Dousset; Frédéric Batteux
Journal:  Am J Pathol       Date:  2010-11-05       Impact factor: 4.307

2.  Cellular Changes Consistent With Epithelial-Mesenchymal Transition and Fibroblast-to-Myofibroblast Transdifferentiation in the Progression of Experimental Endometriosis in Baboons.

Authors:  Qi Zhang; Jie Duan; Mark Olson; Asgerally Fazleabas; Sun-Wei Guo
Journal:  Reprod Sci       Date:  2016-04-12       Impact factor: 3.060

Review 3.  Mechanics of Uterosacral Ligaments: Current Knowledge, Existing Gaps, and Future Directions.

Authors:  Kandace Donaldson; Alyssa Huntington; Raffaella De Vita
Journal:  Ann Biomed Eng       Date:  2021-03-22       Impact factor: 3.934

4.  Neuropeptides Substance P and Calcitonin Gene Related Peptide Accelerate the Development and Fibrogenesis of Endometriosis.

Authors:  Dingmin Yan; Xishi Liu; Sun-Wei Guo
Journal:  Sci Rep       Date:  2019-02-25       Impact factor: 4.379

  4 in total

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