Masano Shimbo1, Norihiko Ito, Kazuaki Kadonosono. 1. Department of Ophthalmology, Yokohama City University, School of Medicine, 3-9 Hukuura, Kanazawa-ku, Yokohama 236-0004, Japan.
Abstract
PURPOSE: beta-D-glucan values in the vitreous were investigated in order to evaluate their usefulness for the diagnosis of fungal endophthalmitis. METHODS: The vitreous or vitreous perfusate were collected from twenty-six patients who underwent vitreous surgery at the Department of Ophthalmology, Yokohama City University, School of Medicine and beta-D-glucan values in these samples were examined. RESULTS: Two samples with fungal endophthalmitis showed remarkably high concentration beta-D-glucan values. The other samples, except one, without fungal endophthalmitis showed significantly low beta-D-glucan values of less than 10.0 pg/ml. CONCLUSION: It is expected that beta-D-glucan values in the vitreous may be more sensitive than culture methods, and may be useful for the diagnosis of fungal endophthalmitis.
PURPOSE:beta-D-glucan values in the vitreous were investigated in order to evaluate their usefulness for the diagnosis of fungal endophthalmitis. METHODS: The vitreous or vitreous perfusate were collected from twenty-six patients who underwent vitreous surgery at the Department of Ophthalmology, Yokohama City University, School of Medicine and beta-D-glucan values in these samples were examined. RESULTS: Two samples with fungal endophthalmitis showed remarkably high concentration beta-D-glucan values. The other samples, except one, without fungal endophthalmitis showed significantly low beta-D-glucan values of less than 10.0 pg/ml. CONCLUSION: It is expected that beta-D-glucan values in the vitreous may be more sensitive than culture methods, and may be useful for the diagnosis of fungal endophthalmitis.