Literature DB >> 12384380

Erythromycin resistance in Borrelia burgdorferi.

Darya Terekhova1, Marina L Sartakova, Gary P Wormser, Ira Schwartz, Felipe C Cabello.   

Abstract

Susceptibility testing of laboratory strains and clinical isolates of Borrelia burgdorferi indicates that resistance to erythromycin is present in them. Evaluation of the MICs, minimal bactericidal concentrations, and kinetics of bacterial killing of erythromycin suggests that this resistance is increased by preexposure to the antibiotic, is dependent on inoculum size, and may be the result of selection of subpopulations of bacterial cells with increased resistance.

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Year:  2002        PMID: 12384380      PMCID: PMC128697          DOI: 10.1128/AAC.46.11.3637-3640.2002

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  18 in total

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  23 in total

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10.  Evidence of a conjugal erythromycin resistance element in the Lyme disease spirochete Borrelia burgdorferi.

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