Literature DB >> 12384374

Propranolol inhibits hyphal development in Candida albicans.

Carol A Baker1, Kevin Desrosiers, Joseph W Dolan.   

Abstract

Propranolol was used to investigate the role of phosphatidic acid (PA) and diacylglycerol in the dimorphic transition in Candida albicans. Propranolol was able to inhibit the appearance of germ tubes without decreasing growth rate. Data suggest that inhibition of morphogenesis may be due to binding by propranolol of PA derived from PLD1 hydrolysis of phosphatidylcholine.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12384374      PMCID： PMC128717          DOI： 10.1128/AAC.46.11.3617-3620.2002

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  18 in total

1.  A rapid method of total lipid extraction and purification.

Authors:  E G BLIGH; W J DYER
Journal:  Can J Biochem Physiol       Date:  1959-08

2.  Phosphatidate phosphatase from Saccharomyces cerevisiae. Isolation of 45- and 104-kDa forms of the enzyme that are differentially regulated by inositol.

Authors:  K R Morlock; J J McLaughlin; Y P Lin; G M Carman
Journal:  J Biol Chem       Date:  1991-02-25       Impact factor: 5.157

Review 3.  Signaling through phosphatidylcholine breakdown.

Authors:  J H Exton
Journal:  J Biol Chem       Date:  1990-01-05       Impact factor: 5.157

4.  Actions of beta-blocking agents on membrane excitability of the lobster giant axon.

Authors:  M Sasa; B P Avner; E X Albuquerque
Journal:  Eur J Pharmacol       Date:  1973-07       Impact factor: 4.432

5.  The role and relevance of phospholipase D1 during growth and dimorphism of Candida albicans.

Authors:  Bernhard Hube; Daniela Hess; Carol A Baker; Martin Schaller; Wilhelm Schäfer; Joseph W Dolan
Journal:  Microbiology       Date:  2001-04       Impact factor: 2.777

6.  Gonadotropin-releasing hormone activates phospholipase D in ovarian granulosa cells. Possible role in signal transduction.

Authors:  M Liscovitch; A Amsterdam
Journal:  J Biol Chem       Date:  1989-07-15       Impact factor: 5.157

7.  Regulation of phosphatidate phosphatase activity from the yeast Saccharomyces cerevisiae by sphingoid bases.

Authors:  W I Wu; Y P Lin; E Wang; A H Merrill; G M Carman
Journal:  J Biol Chem       Date:  1993-07-05       Impact factor: 5.157

8.  Interaction of propranolol with model phospholipid membranes. Monolayer, spin label and fluorescent spectroscopy studies.

Authors:  W K Surewicz; W Leyko
Journal:  Biochim Biophys Acta       Date:  1981-05-06

9.  Isolation of the Candida albicans gene for orotidine-5'-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations.

Authors:  A M Gillum; E Y Tsay; D R Kirsch
Journal:  Mol Gen Genet       Date:  1984

10.  Activation of actin polymerization by phosphatidic acid derived from phosphatidylcholine in IIC9 fibroblasts.

Authors:  K S Ha; J H Exton
Journal:  J Cell Biol       Date:  1993-12       Impact factor: 10.539
View more
  6 in total

1.  Relative risk of vaginal candidiasis after use of antibiotics compared with antidepressants in women.

Authors:  Richard Elliott
Journal:  Drug Saf       Date:  2005       Impact factor: 5.606

Review 2.  Modulation of morphogenesis in Candida albicans by various small molecules.

Authors:  Julie Shareck; Pierre Belhumeur
Journal:  Eukaryot Cell       Date:  2011-06-03

3.  Cellular and molecular biology of Candida albicans estrogen response.

Authors:  Georgina Cheng; Kathleen M Yeater; Lois L Hoyer
Journal:  Eukaryot Cell       Date:  2006-01

4.  Natamycin and Voriconazole Exhibit Synergistic Interactions with Nonantifungal Ophthalmic Agents against Fusarium Species Ocular Isolates.

Authors:  Michael E Zegans; Robert A Cramer; Christiaan A Rees; Ruina Bao
Journal:  Antimicrob Agents Chemother       Date:  2019-06-24       Impact factor: 5.191

5.  Role of actin cytoskeletal dynamics in activation of the cyclic AMP pathway and HWP1 gene expression in Candida albicans.

Authors:  Michael J Wolyniak; Paula Sundstrom
Journal:  Eukaryot Cell       Date:  2007-08-22

6.  Drugs with new lease of life as quorum sensing inhibitors: for combating MDR Acinetobacter baumannii infections.

Authors:  Noura M Seleem; Hemat K Abd El Latif; Moataz A Shaldam; Amira El-Ganiny
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2020-04-23       Impact factor: 3.267
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.