Literature DB >> 12382250

Continuing exposure to hexavalent chromium, a known lung carcinogen: an analysis of OSHA compliance inspections, 1990-2000.

Peter Lurie1, Sidney M Wolfe.   

Abstract

BACKGROUND: Hexavalent chromium is widely recognized to be a lung carcinogen. However, the U.S. Occupational Safety and Health Administration (OSHA) has failed to reduce the permissible exposure limit (PEL), despite having acknowledged in 1994 that the current limit is too high. In 1993, Public Citizen and the Paper, Allied-Industrial, Chemical and Energy Workers International Union (PACE) petitioned to lower the PEL from the current 100 microg/m(3) to 0.5 microg/m(3) as an 8-hr time-weighted average (TWA).
METHODS: To assess industry compliance with the current PEL, and to determine the feasibility of achieving the proposed lower limit of 0.5 microg/m(3), we conducted a secondary data analysis of OSHA's Integrated Management Information System (IMIS) database. This database contains 813 measurements of hexavalent chromium exposure from inspections performed during the years 1990-2000.
RESULTS: There was a statistically significant decline in the annual number of measurements over the study period from 127 in 1990 to 67 in 2000 (F = 0.0009; linear regression). The median TWA measurement was 10 microg/m(3) (range: 0.01-13,960 microg/m(3)) and the median ceiling measurement was 40.5 microg/m(3) (range: 0.25-25,000 microg/m(3)). Neither median TWA nor median ceiling exposures (if hexavalent chromium was detected) declined significantly during the study period (F = 0.065 and 0.57, respectively). Overall, 13.7% of TWA measurements were at or below the Public Citizen/PACE proposed standard; 65.0% were between the Public Citizen/PACE proposal and the current OSHA PEL; and 21.3% exceeded the OSHA PEL. Compared to OSHA measurements, state measurements were less likely to detect hexavalent chromium (40.2% vs. 52.1%; P = 0.0007; chi-square) and less likely to issue any citation (9.3% vs. 19.1%; P = 0.0003), including citations for overexposure if the exposure exceeded the PEL (54.8% vs. 78.8%; P = 0.012).
CONCLUSIONS: U.S. workers continue to be exposed to dangerously high hexavalent chromium levels, but low exposure levels were found in some industries. Further investigations should examine whether state plans provide weaker enforcement than federal OSHA. Copyright 2002 Wiley-Liss, Inc.

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Year:  2002        PMID: 12382250     DOI: 10.1002/ajim.10128

Source DB:  PubMed          Journal:  Am J Ind Med        ISSN: 0271-3586            Impact factor:   2.214


  5 in total

1.  Workplace measurements by the US Occupational Safety and Health Administration since 1979: descriptive analysis and potential uses for exposure assessment.

Authors:  J Lavoue; M C Friesen; I Burstyn
Journal:  Ann Occup Hyg       Date:  2012-09-05

2.  Molecular mechanisms of hexavalent chromium-induced apoptosis in human bronchoalveolar cells.

Authors:  Patrizia Russo; Alessia Catassi; Alfredo Cesario; Andrea Imperatori; Nicola Rotolo; Massimo Fini; Pierluigi Granone; Lorenzo Dominioni
Journal:  Am J Respir Cell Mol Biol       Date:  2005-09-15       Impact factor: 6.914

Review 3.  Toxicity and oxidative stress induced by chromium in workers exposed from different occupational settings around the globe: A review.

Authors:  Muhammad Junaid; Muhammad Zaffar Hashmi; Riffat Naseem Malik; De-Sheng Pei
Journal:  Environ Sci Pollut Res Int       Date:  2016-08-25       Impact factor: 4.223

Review 4.  Selected science: an industry campaign to undermine an OSHA hexavalent chromium standard.

Authors:  David Michaels; Celeste Monforton; Peter Lurie
Journal:  Environ Health       Date:  2006-02-23       Impact factor: 5.984

5.  Heavy Metal Accumulation is Associated with Molecular and Pathological Perturbations in Liver of Variola louti from the Jeddah Coast of Red Sea.

Authors:  Saleh A Mohamed; Mohamed F Elshal; Taha A Kumosani; Ahmad O Mal; Youssri M Ahmed; Yaaser Q Almulaiky; Amer H Asseri; Mazin A Zamzami
Journal:  Int J Environ Res Public Health       Date:  2016-03-21       Impact factor: 3.390

  5 in total

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