Literature DB >> 12382040

The nitrile-degrading enzymes: current status and future prospects.

A Banerjee1, R Sharma, U C Banerjee.   

Abstract

Nitrile-converting enzymes are becoming commonplace in the synthesis of pharmaceuticals and commodity chemicals. These versatile biocatalysts have potential applications in different fields including synthetic biocatalysis and bioremediation. This review attempts to describe in detail the three major classes of nitrile-converting enzymes, namely nitrilases, nitrile hydratases and amidases. Various aspects of these enzymes including their occurrence, mechanism of action, characteristics and applicability in different sectors have been elaborately elucidated. Cloning of genes related to nitrile-converting enzymes is also discussed.

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Year:  2002        PMID: 12382040     DOI: 10.1007/s00253-002-1062-0

Source DB:  PubMed          Journal:  Appl Microbiol Biotechnol        ISSN: 0175-7598            Impact factor:   4.813


  73 in total

Review 1.  Synthetic analogues of cysteinate-ligated non-heme iron and non-corrinoid cobalt enzymes.

Authors:  Julie A Kovacs
Journal:  Chem Rev       Date:  2004-02       Impact factor: 60.622

2.  Structural basis of biological nitrile reduction.

Authors:  Vimbai M Chikwana; Boguslaw Stec; Bobby W K Lee; Valérie de Crécy-Lagard; Dirk Iwata-Reuyl; Manal A Swairjo
Journal:  J Biol Chem       Date:  2012-07-11       Impact factor: 5.157

Review 3.  Development of soil microbiology methods: from respirometry to molecular approaches.

Authors:  Jiří Gabriel
Journal:  J Ind Microbiol Biotechnol       Date:  2010-11-18       Impact factor: 3.346

4.  Immobilization of nitrilase on bioinspired silica for efficient synthesis of 2-hydroxy-4-(methylthio) butanoic acid from 2-hydroxy-4-(methylthio) butanenitrile.

Authors:  Li-Qun Jin; Dong-Jing Guo; Zong-Tong Li; Zhi-Qiang Liu; Yu-Guo Zheng
Journal:  J Ind Microbiol Biotechnol       Date:  2016-02-17       Impact factor: 3.346

5.  The alkyl tert-butyl ether intermediate 2-hydroxyisobutyrate is degraded via a novel cobalamin-dependent mutase pathway.

Authors:  Thore Rohwerder; Uta Breuer; Dirk Benndorf; Ute Lechner; Roland H Müller
Journal:  Appl Environ Microbiol       Date:  2006-06       Impact factor: 4.792

6.  Immobilization of cells with nitrilase activity from a thermophilic bacterial strain.

Authors:  L Kabaivanova; E Dobreva; P Dimitrov; E Emanuilova
Journal:  J Ind Microbiol Biotechnol       Date:  2004-12-23       Impact factor: 3.346

7.  The quaternary structure of the amidase from Geobacillus pallidus RAPc8 is revealed by its crystal packing.

Authors:  Vinod B Agarkar; Serah W Kimani; Donald A Cowan; Muhammed F-R Sayed; B Trevor Sewell
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2006-11-04

8.  Novel sensitive high-throughput screening strategy for nitrilase-producing strains.

Authors:  Qing Zhu; Ao Fan; Yuanshan Wang; Xiaoqin Zhu; Zhao Wang; Minghuo Wu; Yuguo Zheng
Journal:  Appl Environ Microbiol       Date:  2007-08-03       Impact factor: 4.792

9.  Purification and characterization of a thermostable aliphatic amidase from the hyperthermophilic archaeon Pyrococcus yayanosii CH1.

Authors:  Ling Fu; Xuegong Li; Xiang Xiao; Jun Xu
Journal:  Extremophiles       Date:  2014-01-16       Impact factor: 2.395

10.  Identification of an active site-bound nitrile hydratase intermediate through single turnover stopped-flow spectroscopy.

Authors:  Natalie Gumataotao; Misty L Kuhn; Natalia Hajnas; Richard C Holz
Journal:  J Biol Chem       Date:  2013-04-15       Impact factor: 5.157

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