Literature DB >> 123818

Sectinomycin in the treatment of gonorrhoea in females and males.

A H Finger.   

Abstract

126 female patients with proven gonococcal infection were treated with 4 g. spectinomycin bihydrochloride given intramuscularly in a single does. In 120 cases followed up there were four possible treatment failures, giving a cure rate of 97-6 per cent. 99 male patients with acute gonococcal urethritis were treated with a single dose of 2, g. sectinomycin bihydrochloride. Of 88 cases followed up, there were three possible treatment failures, giving a cure rate of 96-6 per cent. Spectinomycin is an important addition to gonorrhoea therapy but should be reserved for penicillin sensitive patients and penicillin insensitive infections.

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Year:  1975        PMID: 123818      PMCID: PMC1045107          DOI: 10.1136/sti.51.1.38

Source DB:  PubMed          Journal:  Br J Vener Dis        ISSN: 0007-134X


  10 in total

1.  Spectinomycin for the treatment of gonorrhoea at Brisbane, Australia.

Authors:  B A Smithurst
Journal:  N Z Med J       Date:  1972-02

2.  Preliminary report on spectinomycin HCl in the treatment of gonorrhoea in homosexual men.

Authors:  W R Holder; D P Roberts; W C Duncan; J M Knox
Journal:  Br J Vener Dis       Date:  1972-08

3.  The treatment of gonorrhea with spectinomycin and rifampicin.

Authors:  R Labowitz; W L Porter; W J Holloway
Journal:  Del Med J       Date:  1970-11

4.  "Trobicin hydrochloride" in the treatment of gonorrhoea.

Authors:  W M Platts
Journal:  Med J Aust       Date:  1970-09-12       Impact factor: 7.738

5.  Spectinomycin hydrochloride in the treatment of uncomplicated gonorrhoea.

Authors:  C E Cornelius; G Domescik
Journal:  Br J Vener Dis       Date:  1970-06

6.  Diagnosis and treatment of gonorrhea in the female.

Authors:  J B Lucas; E V Price; J D Thayer; A Schroeter
Journal:  N Engl J Med       Date:  1967-06-29       Impact factor: 91.245

7.  Spectinomycin hydrochloride (Trobicin) in the treatment of gonorrhoea. Observation of resistant strains of Neisseria gonorrhoeae.

Authors:  A Reyn; H Schmidt; M Trier; M W Bentzon
Journal:  Br J Vener Dis       Date:  1973-02

8.  Treatment of gonorrhea with spectinomycin hydrochloride: comparison with standard penicillin schedules.

Authors:  W C Duncan; W R Holder; D P Roberts; J M Knox
Journal:  Antimicrob Agents Chemother       Date:  1972-03       Impact factor: 5.191

9.  Trobicin (actinospectacin), a new injectable antibiotic in the treatment of gonorrhoea.

Authors:  R R WILLCOX
Journal:  Br J Vener Dis       Date:  1962-09

10.  Treatment of male urethral gonorrhoea with spectinomycin hydrochloride (Trobicin).

Authors:  F Tuza; G Hatos
Journal:  Med J Aust       Date:  1973-12-15       Impact factor: 7.738

  10 in total
  2 in total

1.  Effect of penicillin and spectinomycin given for urethritis and cervicitis with Neisseria gonorrhoeae: high prevalence of penicillin-resistant isolates.

Authors:  Y H Kouri; L González; M Pérez; R Menar; C R Gadea; E Kraiselburd; L J Torres-Bauza
Journal:  Genitourin Med       Date:  1989-10

2.  Epidemiology and treatment of gonorrhoea caused by penicillinase-producing strains of Neisseria gonorrhoeae in Fukuoka, Japan.

Authors:  S Urabe; S I Yoshida; Y Mizuguchi
Journal:  Br J Vener Dis       Date:  1983-02
  2 in total

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