Literature DB >> 12380935

T wave alternans and Torsades de Pointes after the use of intravenous pentamidine.

Christopher R Kroll1, Leonard S Gettes.   

Abstract

We report the case of a patient in whom dramatic T wave alternans with brief bouts of torsades de pointes and QT prolongation occurred in association with intravenously administered pentamidine. This ECG marker of a potentially fatal side effect, although uncommon, should be looked for in patients requiring the use of this drug.

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Year:  2002        PMID： 12380935     DOI： 10.1046/j.1540-8167.2002.00936.x

Source DB:  PubMed          Journal:  J Cardiovasc Electrophysiol        ISSN： 1045-3873


  11 in total

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Review 6.  Micro-electrode arrays in cardiac safety pharmacology: a novel tool to study QT interval prolongation.

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8.  T-wave alternans and arrhythmogenesis in cardiac diseases.

Authors:  Zhilin Qu; Yuanfang Xie; Alan Garfinkel; James N Weiss
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9.  Drug-likeness of linear pentamidine analogues and their impact on the hERG K+ channel - correlation with structural features.

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Journal:  RSC Adv       Date:  2019-12-02       Impact factor: 3.361

10.  Mechanistic insight into spontaneous transition from cellular alternans to arrhythmia-A simulation study.

Authors:  Wei Wang; Shanzhuo Zhang; Haibo Ni; Clifford J Garratt; Mark R Boyett; Jules C Hancox; Henggui Zhang
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