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Literature DB >> 12380686

Chaperones come of age.

Abstract

Chaperone function plays a key role in repairing proteotoxic damage, in the maintenance of cell architecture, and in cell survival. Here, we summarize our current knowledge about changes in chaperone expression and function in the aging process, as well as their involvement in longevity and cellular senescence.

Entities: Disease

Mesh：

Substances：

Year: 2002 PMID： 12380686 PMCID： PMC514816 DOI： 10.1379/1466-1268(2002)007<0186:ccoa>2.0.co;2

Source DB: PubMed Journal: Cell Stress Chaperones ISSN： 1355-8145 Impact factor: 3.667

65 in total

1. Chaperone-percolator model: a possible molecular mechanism of Anfinsen-cage-type chaperones.

Authors: P Csermely
Journal: Bioessays Date: 1999-11 Impact factor: 4.345

2. Protein oxidation in response to increased transcriptional or translational errors.

Authors: S Dukan; A Farewell; M Ballesteros; F Taddei; M Radman; T Nyström
Journal: Proc Natl Acad Sci U S A Date: 2000-05-23 Impact factor: 11.205

Review 3. Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice.

Authors: R Weindruch; T Kayo; C K Lee; T A Prolla
Journal: J Nutr Date: 2001-03 Impact factor: 4.798

Review 4. Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases.

Authors: M Y Sherman; A L Goldberg
Journal: Neuron Date: 2001-01 Impact factor: 17.173

5. Age-related decline in chaperone-mediated autophagy.

Authors: A M Cuervo; J F Dice
Journal: J Biol Chem Date: 2000-10-06 Impact factor: 5.157

6. Age-related alterations in the activation of heat shock transcription factor 1 in rat hepatocytes.

Authors: A R Heydari; S You; R Takahashi; A Gutsmann-Conrad; K D Sarge; A Richardson
Journal: Exp Cell Res Date: 2000-04-10 Impact factor: 3.905

7. Increasing Saccharomyces cerevisiae stress resistance, through the overactivation of the heat shock response resulting from defects in the Hsp90 chaperone, does not extend replicative life span but can be associated with slower chronological ageing of nondividing cells.

Authors: N Harris; M MacLean; K Hatzianthis; B Panaretou; P W Piper
Journal: Mol Genet Genomics Date: 2001-04 Impact factor: 3.291

8. Dietary restriction and aging in rhesus monkeys: the University of Wisconsin study.

Authors: J J Ramsey; R J Colman; N C Binkley; J D Christensen; T A Gresl; J W Kemnitz; R Weindruch
Journal: Exp Gerontol Date: 2000-12 Impact factor: 4.032

9. Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2.

Authors: J Nylandsted; M Rohde; K Brand; L Bastholm; F Elling; M Jäättelä
Journal: Proc Natl Acad Sci U S A Date: 2000-07-05 Impact factor: 11.205

10. Increased hsp22 RNA levels in Drosophila lines genetically selected for increased longevity.

Authors: R Kurapati; H B Passananti; M R Rose; J Tower
Journal: J Gerontol A Biol Sci Med Sci Date: 2000-11 Impact factor: 6.053

13 in total

1. Serum and lymphocyte levels of heat shock protein 70 in aging: a study in the normal Chinese population.

Authors: Xingfang Jin; Ruibo Wang; Chengfeng Xiao; Longxian Cheng; Feng Wang; Li Yang; Taoyi Feng; Ming Chen; Sheng Chen; Xiaoye Fu; Jie Deng; Ru Wang; Fangfang Tang; Qingyi Wei; Robert M Tanguay; Tangchun Wu
Journal: Cell Stress Chaperones Date: 2004-03 Impact factor: 3.667

2. Aging modulates susceptibility to mouse liver Mallory-Denk body formation.

Authors: Shinichiro Hanada; Masaru Harada; Mitsuhiko Abe; Jun Akiba; Masahiro Sakata; Raymond Kwan; Eitaro Taniguchi; Takumi Kawaguchi; Hironori Koga; Eisuke Nagata; Takato Ueno; Michio Sata
Journal: J Histochem Cytochem Date: 2012-04-03 Impact factor: 2.479

3. Allosteric drugs: the interaction of antitumor compound MKT-077 with human Hsp70 chaperones.

Authors: Aikaterini Rousaki; Yoshinari Miyata; Umesh K Jinwal; Chad A Dickey; Jason E Gestwicki; Erik R P Zuiderweg
Journal: J Mol Biol Date: 2011-06-25 Impact factor: 5.469

4. Differences in the chaperone-like activities of the four main small heat shock proteins of Drosophila melanogaster.

Authors: Geneviève Morrow; John J Heikkila; Robert M Tanguay
Journal: Cell Stress Chaperones Date: 2006 Impact factor: 3.667

5. The Hsp60C gene in the 25F cytogenetic region in Drosophila melanogaster is essential for tracheal development and fertility.

Authors: Surajit Sarkar; Subhash C Lakhotia
Journal: J Genet Date: 2005-12 Impact factor: 1.166

6. Cloning, characterization, and functional studies of a human 40-kDa catecholamine-regulated protein: implications in central nervous system disorders.

Authors: Joseph Gabriele; Giuseppe F Pontoriero; Nancy Thomas; Christy A Thomson; Kevin Skoblenick; Zdenek B Pristupa; Ram K Mishra
Journal: Cell Stress Chaperones Date: 2009-03-12 Impact factor: 3.667

7. Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration.

Authors: Peter Barabas; Aihua Liu; Wei Xing; Ching-Kang Chen; Zongzhong Tong; Carl B Watt; Bryan W Jones; Paul S Bernstein; David Križaj
Journal: Proc Natl Acad Sci U S A Date: 2013-03-11 Impact factor: 11.205