| Literature DB >> 12379233 |
Gianluca Occhi1, Alessandra Rampazzo, Giorgia Beffagna, Gian Antonio Danieli.
Abstract
Three neurexin (NRXN) genes are known in humans, each transcribed from two promoters and extensively spliced at five canonical positions, thus generating thousands of isoforms. For NRXN3, only neuronal expression was reported so far. We reported here on the expression of NRXN3 in additional tissues (lung, pancreas, heart, placenta, liver, and kidney) and on the identification and characterization of heart-specific splicing variants of NRXN3. Cardiac isoforms of NRXN3 probably participate in a complex involving dystroglycan and proteins of extracellular matrix, involved in intercellular connections.Entities:
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Year: 2002 PMID： 12379233 DOI： 10.1016/s0006-291x(02)02403-8
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575