Literature DB >> 1237822

Essential tremor: treatment with propranolol.

E S Tolosa, R B Loewenson.   

Abstract

A double-blind trial of propranolol, in a dosage of 120 mg a day, and placebo was conducted in 11 patients with essential tremor. An improvement in tremor was observed in all patients who received propranolol and was most pronounced in the upper extremities. The favorable clinical assessment was further confirmed by improvement in a grooved pegboard test and in the quality of handwriting as evaluated by two "blind" observers. No side effects were encountered. It is concluded that propranolol is at present the best available drug for the treatment of essential tremor.

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Year:  1975        PMID: 1237822     DOI: 10.1212/wnl.25.11.1041

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  21 in total

Review 1.  Essential tremor.

Authors:  Joaquim Jos Ferreira; Cristina Sampaio
Journal:  BMJ Clin Evid       Date:  2007-05-01

Review 2.  Pharmacotherapy of essential tremor : an overview of existing and upcoming agents.

Authors:  Kelly E Lyons; Rajesh Pahwa
Journal:  CNS Drugs       Date:  2008       Impact factor: 5.749

3.  Physiological and pharmacological aids in the differential diagnosis of tremor.

Authors:  B T Shahani; R R Young
Journal:  J Neurol Neurosurg Psychiatry       Date:  1976-08       Impact factor: 10.154

4.  Beta-adrenoreceptor mechanisms in essential tremor: a comparative single dose study of the effect of a non-selective and a beta-2 selective adrenoreceptor antagonist.

Authors:  L Cleeves; L J Findley
Journal:  J Neurol Neurosurg Psychiatry       Date:  1984-09       Impact factor: 10.154

5.  beta-Adrenoreceptor antagonists in essential tremor.

Authors:  D Jefferson; P Jenner; C D Marsden
Journal:  J Neurol Neurosurg Psychiatry       Date:  1979-10       Impact factor: 10.154

6.  Benign familial tremor treated with primidone.

Authors:  G Procaccianti; P Martinelli; A Baruzzi; P Pazzaglia; E Lugarezi
Journal:  Br Med J (Clin Res Ed)       Date:  1981-08-22

Review 7.  Essential tremor.

Authors:  T J Murray
Journal:  Can Med Assoc J       Date:  1981-06-15       Impact factor: 8.262

8.  Relationship between plasma propranolol concentration and relief of essential tremor.

Authors:  D Jefferson; P Jenner; C D Marsden
Journal:  J Neurol Neurosurg Psychiatry       Date:  1979-09       Impact factor: 10.154

Review 9.  Benefits and risks of pharmacological treatments for essential tremor.

Authors:  Kelly E Lyons; Rajesh Pahwa; Cynthia L Comella; Mahmood S Eisa; Rodger J Elble; Stanley Fahn; Joseph Jankovic; Jorge L Juncos; William C Koller; William G Ondo; Kapil D Sethi; Matthew B Stern; Caroline M Tanner; Ron Tintner; Ray L Watts
Journal:  Drug Saf       Date:  2003       Impact factor: 5.606

Review 10.  Treatment of essential tremor: a systematic review of evidence and recommendations from the Italian Movement Disorders Association.

Authors:  Mario Zappia; Alberto Albanese; Elisa Bruno; Carlo Colosimo; Graziella Filippini; Paolo Martinelli; Alessandra Nicoletti; Graziella Quattrocchi; Giovanni Abbruzzese; Alfredo Berardelli; Roberta Allegra; Maria Stella Aniello; Antonio E Elia; Davide Martino; Daniela Murgia; Marina Picillo; Giovanna Squintani
Journal:  J Neurol       Date:  2012-08-11       Impact factor: 4.849

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