Literature DB >> 12378110

Resection for pancreatic cancer in the new millennium.

Ake Andrén-Sandberg1, John P Neoptolemos.   

Abstract

BACKGROUND AND AIM OF THE STUDY: Complications of pancreatic resections are dangerous and costly. A literature review was therefore done to investigate the evidence for improving the results by regionalizing this demanding surgery.
RESULTS: Studies from four countries (USA, UK, the Netherlands and Finland) with advanced health care systems have shown a significant inverse correlation between case volume for pancreatic cancer resection and post-operative mortality. Further analysis reveals lower complications, reduced hospital stay, reduced hospital costs and improved survival of patients treated in high-volume hospitals. The relationship volume and outcome is with institutional volume rather than single surgeon caseload. The evidence therefore strongly supports the regionalization of pancreatic cancer surgery into large specialized multi-disciplinary units. In the UK, the National Health Service Executive has instructed Regional Health Authorities to concentrate pancreatic cancer surgery into designated Regional Centres ideally with catchment populations of 2-4 million. There is now considerable pressure to adopt a similar policy in all countries with advanced health care systems.
CONCLUSION: There is today enough evidence to advocate the regionalization of pancreatic cancer resections. Copyright 2002 S. Karger AG, Basel and IAP

Entities:  

Mesh:

Year:  2002        PMID: 12378110     DOI: 10.1159/000064710

Source DB:  PubMed          Journal:  Pancreatology        ISSN: 1424-3903            Impact factor:   3.996


  10 in total

Review 1.  Trials of gene therapy for pancreatic carcinoma.

Authors:  Christopher M Halloran; Paula Ghaneh; Eithne Costello; John P Neoptolemos
Journal:  Curr Gastroenterol Rep       Date:  2005-06

Review 2.  Gastroenterology services in the UK. The burden of disease, and the organisation and delivery of services for gastrointestinal and liver disorders: a review of the evidence.

Authors:  J G Williams; S E Roberts; M F Ali; W Y Cheung; D R Cohen; G Demery; A Edwards; M Greer; M D Hellier; H A Hutchings; B Ip; M F Longo; I T Russell; H A Snooks; J C Williams
Journal:  Gut       Date:  2007-02       Impact factor: 23.059

Review 3.  No-touch isolation techniques for pancreatic cancer.

Authors:  Tamotsu Kuroki; Susumu Eguchi
Journal:  Surg Today       Date:  2016-03-01       Impact factor: 2.549

Review 4.  Development of an integrated pancreatic disease service.

Authors:  James A Jupp; Colin D Johnson; Fanny W Shek; David R Fine
Journal:  Frontline Gastroenterol       Date:  2011-01-09

5.  Preoperative staging and evaluation of resectability in pancreatic ductal adenocarcinoma.

Authors:  R Andersson; C E Vagianos; R C N Williamson
Journal:  HPB (Oxford)       Date:  2004       Impact factor: 3.647

Review 6.  [New aspects of surgery for pancreatic cancer. Principles, results and evidence].

Authors:  M Distler; R Grützmann
Journal:  Pathologe       Date:  2012-11       Impact factor: 1.011

7.  Pancreatic resection for intraductal papillary mucinous neoplasm- a thirteen-year single center experience.

Authors:  Katharina Marsoner; Johannes Haybaeck; Dora Csengeri; James Elvis Waha; Jakob Schagerl; Rainer Langeder; Hans Joerg Mischinger; Peter Kornprat
Journal:  BMC Cancer       Date:  2016-11-04       Impact factor: 4.430

8.  Evaluation of survival in patients after pancreatic head resection for ductal adenocarcinoma.

Authors:  Marius Distler; Felix Rückert; Maximilian Hunger; Stephan Kersting; Christian Pilarsky; Hans-Detlev Saeger; Robert Grützmann
Journal:  BMC Surg       Date:  2013-04-22       Impact factor: 2.102

9.  Survival from cancer of the pancreas in England and Wales up to 2001.

Authors:  N Starling; D Cunningham
Journal:  Br J Cancer       Date:  2008-09-23       Impact factor: 7.640

10.  Portal vein resection in advanced pancreatic adenocarcinoma: is it worth the risk?

Authors:  Katharina Marsoner; Rainer Langeder; Dora Csengeri; Gottfried Sodeck; Hans Jörg Mischinger; Peter Kornprat
Journal:  Wien Klin Wochenschr       Date:  2016-06-30       Impact factor: 1.704

  10 in total

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