Literature DB >> 12375993

Functionalized pyridylboronic acids and their Suzuki cross-coupling reactions to yield novel heteroarylpyridines.

Paul R Parry1, Changsheng Wang, Andrei S Batsanov, Martin R Bryce, Brian Tarbit.   

Abstract

2-Bromo-5-pyridylboronic acid 2a, 2-chloro-5-pyridylboronic acid 2b, 2-methoxy-5-pyridylboronic acid 2c, and 5-chloro-2-methoxy-4-pyridylboronic acid 4 have been synthesized and shown to undergo palladium-catalyzed cross-coupling reactions with heteroaryl bromides to yield novel heteroarylpyridine derivatives. The X-ray crystal structures of 2a and 2b have been obtained.

Entities:  

Year:  2002        PMID： 12375993     DOI： 10.1021/jo020388b

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  9 in total

1.  One-pot Double Suzuki Couplings of Dichloropyrimidines.

Authors:  Samantha C Anderson; Scott T Handy
Journal:  Synthesis (Stuttg)       Date:  2010-08-01       Impact factor: 3.157

2.  tert-Butyl 2-(dihydroxyboryl)pyrrole-1-carboxylate.

Authors:  Tomasz Klis; Janusz Serwatowski
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-05-10

3.  A computational characterization of boron-oxygen multiple bonding in HN=CH-CH=CH-NH-BO.

Authors:  Joseph D Larkin; Krishna L Bhat; George D Markham; Tony D James; Bernard R Brooks; Charles W Bock
Journal:  J Phys Chem A       Date:  2008-08-15       Impact factor: 2.781

4.  Computational investigation of the oxidative deboronation of boroglycine, H2N-CH2-B(OH)2, Using H2O and H2O2.

Authors:  Joseph D Larkin; George D Markham; Matt Milkevitch; Bernard R Brooks; Charles W Bock
Journal:  J Phys Chem A       Date:  2009-10-15       Impact factor: 2.781

5.  Site-selective Suzuki-Miyaura coupling of heteroaryl halides - understanding the trends for pharmaceutically important classes.

Authors:  Joshua Almond-Thynne; David C Blakemore; David C Pryde; Alan C Spivey
Journal:  Chem Sci       Date:  2016-08-09       Impact factor: 9.825

6.  Efficient Synthesis of Novel Pyridine-Based Derivatives via Suzuki Cross-Coupling Reaction of Commercially Available 5-Bromo-2-methylpyridin-3-amine: Quantum Mechanical Investigations and Biological Activities.

Authors:  Gulraiz Ahmad; Nasir Rasool; Hafiz Mansoor Ikram; Samreen Gul Khan; Tariq Mahmood; Khurshid Ayub; Muhammad Zubair; Eman Al-Zahrani; Usman Ali Rana; Muhammad Nadeem Akhtar; Noorjahan Banu Alitheen
Journal:  Molecules       Date:  2017-01-27       Impact factor: 4.411

Review 7.  Recent advance in heterocyclic organozinc and organomanganese compounds; direct synthetic routes and application in organic synthesis.

Authors:  Seung-Hoi Kim; Reuben D Rieke
Journal:  Molecules       Date:  2010-11-08       Impact factor: 4.411

8.  Synthesis and Anticancer Activity of Mitotic-Specific 3,4-Dihydropyridine-2(1H)-thiones.

Authors:  Magdalena Perużyńska; Aleksandra Borzyszkowska-Ledwig; Jacek G Sośnicki; Łukasz Struk; Tomasz J Idzik; Gabriela Maciejewska; Łukasz Skalski; Katarzyna Piotrowska; Paweł Łukasik; Marek Droździk; Mateusz Kurzawski
Journal:  Int J Mol Sci       Date:  2021-02-28       Impact factor: 5.923

9.  One Pot Selective Arylation of 2-Bromo-5-Chloro Thiophene; Molecular Structure Investigation via Density Functional Theory (DFT), X-ray Analysis, and Their Biological Activities.

Authors:  Nasir Rasool; Aqsa Kanwal; Tehmina Rasheed; Quratulain Ain; Tariq Mahmood; Khurshid Ayub; Muhammad Zubair; Khalid Mohammed Khan; Muhammad Nadeem Arshad; Abdullah M Asiri; Muhammad Zia-Ul-Haq; Hawa Z E Jaafar
Journal:  Int J Mol Sci       Date:  2016-06-28       Impact factor: 5.923
  9 in total

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