Literature DB >> 12375930

Studies on the biomimetic synthesis of SNF4435 C and D.

John E Moses1, Jack E Baldwin, Rodolfo Marquez, Robert M Adlington, Andrew R Cowley.   

Abstract

[reaction: see text] The biomimetic synthesis of the bicyclic core of the novel immunosuppresants SNF4435C and SNF4435D is reported. The core framework was efficiently generated from the all-trans tetraene precursor in one step and in good yield.

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Year:  2002        PMID： 12375930     DOI： 10.1021/ol020157r

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Total synthesis of the potent androgen receptor antagonist (-)-arabilin: a strategic, biomimetic [1,7]-hydrogen shift.

Authors:  Hee Nam Lim; Kathlyn A Parker
Journal:  J Am Chem Soc       Date:  2011-11-29       Impact factor: 15.419

2.  Mechanistic Studies of Pd(II)-Catalyzed E/Z Isomerization of Unactivated Alkenes: Evidence for a Monometallic Nucleopalladation Pathway.

Authors:  Rei Matsuura; Malkanthi K Karunananda; Mingyu Liu; Nhi Nguyen; Donna G Blackmond; Keary M Engle
Journal:  ACS Catal       Date:  2021-03-19       Impact factor: 13.084

3.  Terminal substituent effects on the reactivity, thermodynamics, and stereoselectivity of the 8π-6π electrocyclization cascades of 1,3,5,7-tetraenes.

Authors:  Ashay Patel; K N Houk
Journal:  J Org Chem       Date:  2014-11-17       Impact factor: 4.354

4.  Total synthesis of endiandric acid J and beilcyclone A from cyclooctatetraene.

Authors:  Oussama Yahiaoui; Adrian Almass; Thomas Fallon
Journal:  Chem Sci       Date:  2020-07-29       Impact factor: 9.825

5.  Palladium hydride promoted stereoselective isomerization of unactivated di(exo)methylenes to endocyclic dienes.

Authors:  Michael E Jung; Gloria S Lee; Hung V Pham; K N Houk
Journal:  Org Lett       Date:  2014-04-11       Impact factor: 6.005
  5 in total

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