| Literature DB >> 12375885 |
Kelvin H Yong1, Nicholas J Taylor, J Michael Chong.
Abstract
[reaction: see text] Dialkylmagnesiums react with chiral secondary amines to form chiral organomagnesium amides (COMAs). These reagents alkylate aldehydes to form secondary alcohols with enantioselectivities up to 91:9 er.Entities:
Year: 2002 PMID： 12375885 DOI： 10.1021/ol0258132
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005