Literature DB >> 12374383

New dithiolopyrrolone antibiotics from Saccharothrix sp. SA 233. II. Physicochemical properties and structure elucidation.

Lynda Lamari1, Abdelghani Zitouni, Tahar Dob, Nasserdine Sabaou, Ahmed Lebrihi, Pierre Germain, Elisabeth Seguin, François Tillequin.   

Abstract

Three new natural dithiopyrrolone antibiotics, 3-methyl-2-butenoylpyrrothine (1), tigloylpyrrothine (2), and n-butyropyrrothine (3) were isolated along with the known isobutyropyrrothine (4) and thiolutin (5) from the fermentation broth of Saccharothrix sp. SA 233. The structures of the novel compounds were established on the basis on their spectral data.

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Year:  2002        PMID： 12374383     DOI： 10.7164/antibiotics.55.702

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  9 in total

1.  Identification of the gene cluster for the dithiolopyrrolone antibiotic holomycin in Streptomyces clavuligerus.

Authors:  Bo Li; Christopher T Walsh
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-01       Impact factor: 11.205

2.  Optimization of the fermentation process of actinomycete strain hhs.015.

Authors:  Xinxuan Wang; Lili Huang; Zhensheng Kang; Heinrich Buchenauer; Xiaoning Gao
Journal:  J Biomed Biotechnol       Date:  2010-05-24

Review 3.  Dithiolopyrrolones: biosynthesis, synthesis, and activity of a unique class of disulfide-containing antibiotics.

Authors:  Bo Li; Walter J Wever; Christopher T Walsh; Albert A Bowers
Journal:  Nat Prod Rep       Date:  2014-07       Impact factor: 13.423

4.  Thiasporines A-C, thiazine and thiazole derivatives from a marine-derived Actinomycetospora chlora.

Authors:  Peng Fu; John B MacMillan
Journal:  J Nat Prod       Date:  2015-01-13       Impact factor: 4.050

5.  A rhodanese-like protein is highly overrepresented in the mutant S. clavuligerus oppA2::aph: effect on holomycin and other secondary metabolites production.

Authors:  Nuria Nárdiz; Irene Santamarta; Luis M Lorenzana; Juan F Martín; Paloma Liras
Journal:  Microb Biotechnol       Date:  2010-11-02       Impact factor: 5.813

6.  Bioprospecting of Soil-Derived Actinobacteria Along the Alar-Hotan Desert Highway in the Taklamakan Desert.

Authors:  Shaowei Liu; Ting Wang; Qinpei Lu; Feina Li; Gang Wu; Zhongke Jiang; Xugela Habden; Lin Liu; Xiaolin Zhang; Dmitry A Lukianov; Ilya A Osterman; Petr V Sergiev; Olga A Dontsova; Chenghang Sun
Journal:  Front Microbiol       Date:  2021-03-15       Impact factor: 5.640

Review 7.  Dithiolopyrrolone natural products: isolation, synthesis and biosynthesis.

Authors:  Zhiwei Qin; Sheng Huang; Yi Yu; Hai Deng
Journal:  Mar Drugs       Date:  2013-10-17       Impact factor: 5.118

Review 8.  Actinobacteria Derived from Algerian Ecosystems as a Prominent Source of Antimicrobial Molecules.

Authors:  Ibtissem Djinni; Andrea Defant; Mouloud Kecha; Ines Mancini
Journal:  Antibiotics (Basel)       Date:  2019-10-01

9.  Unique Cyclized Thiolopyrrolones from the Marine-Derived Streptomyces sp. BTBU20218885.

Authors:  Fuhang Song; Jiansen Hu; Xinwan Zhang; Wei Xu; Jinpeng Yang; Shaoyong Li; Xiuli Xu
Journal:  Mar Drugs       Date:  2022-03-18       Impact factor: 5.118
  9 in total

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