Literature DB >> 12374195

Ceramide in apoptosis: a revisited role.

Thierry Levade1, Sophie Malagarie-Cazenave, Valérie Gouazé, Bruno Ségui, Claudine Tardy, Susan Betito, Nathalie Andrieu-Abadie, Olivier Cuvillier.   

Abstract

The sphingolipid ceramide has recently emerged as a new transducer or modulator of apoptotic cell death. This function, however, has recently been challenged. Here, in the light of recent observations, the role of ceramide in apoptosis signaling is discussed.

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Year:  2002        PMID： 12374195     DOI： 10.1023/a:1020215815013

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  93 in total

1.  Oxidative stress-induced activation of Lyn recruits sphingomyelinase and is requisite for its stimulation by Ara-C.

Authors:  C Bezombes; I Plo; V Mansat-De Mas; A Quillet-Mary; A Nègre-Salvayre; G Laurent; J P Jaffrézou
Journal:  FASEB J       Date:  2001-07       Impact factor: 5.191

2.  Vectorial budding of vesicles by asymmetrical enzymatic formation of ceramide in giant liposomes.

Authors:  J M Holopainen; M I Angelova; P K Kinnunen
Journal:  Biophys J       Date:  2000-02       Impact factor: 4.033

Review 3.  Ceramide in the eukaryotic stress response.

Authors:  Y A Hannun; C Luberto
Journal:  Trends Cell Biol       Date:  2000-02       Impact factor: 20.808

4.  Stress-induced apoptosis is not mediated by endolysosomal ceramide.

Authors:  B Ségui; C Bezombes; E Uro-Coste; J A Medin; N Andrieu-Abadie; N Augé; A Brouchet; G Laurent; R Salvayre; J P Jaffrézou; T Levade
Journal:  FASEB J       Date:  2000-01       Impact factor: 5.191

5.  Influence of Bcl-2 overexpression on the ceramide pathway in daunorubicin-induced apoptosis of leukemic cells.

Authors:  M Allouche; A Bettaieb; C Vindis; A Rousse; C Grignon; G Laurent
Journal:  Oncogene       Date:  1997-04-17       Impact factor: 9.867

6.  Restoration of TNF-alpha-induced ceramide generation and apoptosis in resistant human leukemia KG1a cells by the P-glycoprotein blocker PSC833.

Authors:  C Bezombes; N Maestre; G Laurent; T Levade; A Bettaïeb; J P Jaffrézou
Journal:  FASEB J       Date:  1998-01       Impact factor: 5.191

7.  Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals.

Authors:  R Bose; M Verheij; A Haimovitz-Friedman; K Scotto; Z Fuks; R Kolesnick
Journal:  Cell       Date:  1995-08-11       Impact factor: 41.582

8.  Cytokine response modifier A (CrmA) inhibits ceramide formation in response to tumor necrosis factor (TNF)-alpha: CrmA and Bcl-2 target distinct components in the apoptotic pathway.

Authors:  G S Dbaibo; D K Perry; C J Gamard; R Platt; G G Poirier; L M Obeid; Y A Hannun
Journal:  J Exp Med       Date:  1997-02-03       Impact factor: 14.307

9.  Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation.

Authors:  A Haimovitz-Friedman; C Cordon-Cardo; S Bayoumy; M Garzotto; M McLoughlin; R Gallily; C K Edwards; E H Schuchman; Z Fuks; R Kolesnick
Journal:  J Exp Med       Date:  1997-12-01       Impact factor: 14.307

10.  Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis.

Authors:  A Haimovitz-Friedman; C C Kan; D Ehleiter; R S Persaud; M McLoughlin; Z Fuks; R N Kolesnick
Journal:  J Exp Med       Date:  1994-08-01       Impact factor: 14.307
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  17 in total

1.  Light at the End of the "TUNEL"? Role of Ceramide in Seizure-induced Programmed Cell Death.

Authors:  Carl E. Stafstrom
Journal:  Epilepsy Curr       Date:  2003-09       Impact factor: 7.500

2.  Mechanisms involved in ceramide-induced cell cycle arrest in human hepatocarcinoma cells.

Authors:  Jing Wang; Xiao-Wen Lv; Jie-Ping Shi; Xiao-Song Hu
Journal:  World J Gastroenterol       Date:  2007-02-21       Impact factor: 5.742

3.  A novel mitochondrial sphingomyelinase in zebrafish cells.

Authors:  Takeshi Yabu; Akio Shimuzu; Michiaki Yamashita
Journal:  J Biol Chem       Date:  2009-05-08       Impact factor: 5.157

4.  Retinal sphingolipids and their very-long-chain fatty acid-containing species.

Authors:  Richard S Brush; Julie-Thu A Tran; Kimberly R Henry; Mark E McClellan; Michael H Elliott; Md Nawajes A Mandal
Journal:  Invest Ophthalmol Vis Sci       Date:  2010-04-14       Impact factor: 4.799

5.  p38 mitogen-activated protein kinase/activator protein-1 involved in serum deprivation-induced human alkaline ceramidase 2 upregulation.

Authors:  Zhaoquan Huang; Guojin Huang; Quanzhong Li; Junfei Jin
Journal:  Biomed Rep       Date:  2014-12-02

6.  Golgi fragmentation is associated with ceramide-induced cellular effects.

Authors:  Wei Hu; Ruijuan Xu; Guofeng Zhang; Junfei Jin; Zdzislaw M Szulc; Jacek Bielawski; Yusuf A Hannun; Lina M Obeid; Cungui Mao
Journal:  Mol Biol Cell       Date:  2005-01-12       Impact factor: 4.138

7.  Ceramides: branched alkyl chains in the sphingolipid siblings of diacylglycerol improve biological potency.

Authors:  Ji-Hye Kang; Himanshu Garg; Dina M Sigano; Nicholas Francella; Robert Blumenthal; Victor E Marquez
Journal:  Bioorg Med Chem       Date:  2009-01-11       Impact factor: 3.641

8.  Ceramide production associated with retinal apoptosis after retinal detachment.

Authors:  Marie-Laure Ranty; Stéphane Carpentier; Maxime Cournot; Isabelle Rico-Lattes; François Malecaze; Thierry Levade; Marie-Bernadette Delisle; Jean-Claude Quintyn
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2008-10-29       Impact factor: 3.117

9.  Ceramide metabolite, not intact ceramide molecule, may be responsible for cellular toxicity.

Authors:  Kou-Yi Tserng; Ronda L Griffin
Journal:  Biochem J       Date:  2004-06-15       Impact factor: 3.857

10.  Exosomal lipids impact notch signaling and induce death of human pancreatic tumoral SOJ-6 cells.

Authors:  Sadia Beloribi; Elodie Ristorcelli; Gilles Breuzard; Françoise Silvy; Justine Bertrand-Michel; Evelyne Beraud; Alain Verine; Dominique Lombardo
Journal:  PLoS One       Date:  2012-10-19       Impact factor: 3.240
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