Literature DB >> 12373653

[Preventive and therapeutic attitude in post-traumatic epileptic seizures].

J Sancho-Rieger1, J Parra-Martínez.   

Abstract

INTRODUCTION AND DEVELOPMENT: Due to the vast number of different circumstances surrounding them, the frequency with which post traumatic epileptic seizures occur varies greatly from study to study. Immediate and early epileptic seizures, within a week of the traumatism having taken place, are usually of little importance as regards the risk of post traumatic seizures. The most important factors governing the presentation of post traumatic seizures have to do with the seriousness of the injury, the extension of the brain tissue that is affected and the penetrating nature of the brain traumatism.
CONCLUSION: Although antiepileptic medication significantly reduces the risk of early seizures from occurring, a review of well designed clinical trials has found no evidence that these drugs reduce the morbidity and mortality associated with head injuries, or the appearance of late seizures.

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Year:  2002        PMID: 12373653

Source DB:  PubMed          Journal:  Rev Neurol        ISSN: 0210-0010            Impact factor:   0.870


  2 in total

1.  Pyrazolo[4,3-c]pyridine-4-one (PP-4-one) Exhibits Anti-Epileptogenic Effect in Rat Model of Traumatic Epilepsy by Mammalian Target of Rapamycin (mTOR) Signaling Pathway Downregulation.

Authors:  Jungong Jin; Xi Shen; Lu Tian; Guoyishi He; Ying Zhang
Journal:  Med Sci Monit       Date:  2020-07-20

2.  Rapamycin provides anti-epileptogenic effect in a rat model of post-traumatic epilepsy via deactivation of mTOR signaling pathway.

Authors:  Feng Wang; Fuxiang Chen; Genbo Wang; Shushan Wei; Fu Fang; Dezhi Kang; Yuanxiang Lin
Journal:  Exp Ther Med       Date:  2018-03-28       Impact factor: 2.447

  2 in total

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