Literature DB >> 12372505

Aminoalkoxybiphenylnitriles as histamine-3 receptor ligands.

Ramin Faghih1, Wesley Dwight, Anil Vasudevan, Jurgen Dinges, Scott E Conner, Timothy A Esbenshade, Youssef L Bennani, Arthur A Hancock.   

Abstract

Biaryl nitrile amines were prepared and found to have high affinity and selectivity for human and rat histamine H(3) receptors.

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Year:  2002        PMID： 12372505     DOI： 10.1016/s0960-894x(02)00648-0

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  Detection of multiple H3 receptor affinity states utilizing [3H]A-349821, a novel, selective, non-imidazole histamine H3 receptor inverse agonist radioligand.

Authors:  David G Witte; Betty Bei Yao; Thomas R Miller; Tracy L Carr; Steven Cassar; Rahul Sharma; Ramin Faghih; Bruce W Surber; Timothy A Esbenshade; Arthur A Hancock; Kathleen M Krueger
Journal:  Br J Pharmacol       Date:  2006-05-22       Impact factor: 8.739

2.  Generation of a homology model of the human histamine H(3) receptor for ligand docking and pharmacophore-based screening.

Authors:  Birgit Schlegel; Christian Laggner; Rene Meier; Thierry Langer; David Schnell; Roland Seifert; Holger Stark; Hans-Dieter Höltje; Wolfgang Sippl
Journal:  J Comput Aided Mol Des       Date:  2007-08-01       Impact factor: 3.686
  2 in total

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