| Literature DB >> 12372499 |
Albert W Garofalo1, David W G Wone, Angela Phuc, James E Audia, Cheryl A Bales, Harry F Dovey, Darren B Dressen, Beverly Folmer, Erich G Goldbach, Ashley C Guinn, Lee H Latimer, Thomas E Mabry, Jeffrey S Nissen, Michael A Pleiss, Stephen Sohn, Eugene D Thorsett, Jay S Tung, Jing Wu.
Abstract
Potent, small molecule A beta inhibitors have been prepared that incorporate an alanine core bracketed by an N-terminal arylacetyl group and various C-terminal amino alcohols. The compounds exhibit stereospecific inhibition as demonstrated in an in vitro assay.Entities:
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Year: 2002 PMID： 12372499 DOI： 10.1016/s0960-894x(02)00684-4
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823