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Literature DB >> 1237082

Importance of the aromatic ring in adrenergic amines. Nonaromatic analoques of phenylethanolamine as substrates for phenylethanolamine N-methyltransferase.

G L Grunewald, J M Grindel, W C Vincek, R T Borchardt.

Abstract

Entities: Chemical Gene

Mesh：

Substances：

Year: 1975 PMID： 1237082

Source DB: PubMed Journal: Mol Pharmacol ISSN： 0026-895X Impact factor: 4.436

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1 in total

1. Structure-Based Drug Design of Bisubstrate Inhibitors of Phenylethanolamine N-Methyltransferase Possessing Low Nanomolar Affinity at Both Substrate Binding Domains¹.

Authors: Jian Lu; Aaron G Bart; Qian Wu; Kevin R Criscione; Michael J McLeish; Emily E Scott; Gary L Grunewald
Journal: J Med Chem Date: 2020-11-04 Impact factor: 8.039

1 in total

Importance of the aromatic ring in adrenergic amines. Nonaromatic analoques of phenylethanolamine as substrates for phenylethanolamine N-methyltransferase.

1. Structure-Based Drug Design of Bisubstrate Inhibitors of Phenylethanolamine N-Methyltransferase Possessing Low Nanomolar Affinity at Both Substrate Binding Domains1.

1. Structure-Based Drug Design of Bisubstrate Inhibitors of Phenylethanolamine N-Methyltransferase Possessing Low Nanomolar Affinity at Both Substrate Binding Domains¹.