Literature DB >> 12370025

The use of DODT as a non-malodorous scavenger in Fmoc-based peptide synthesis.

A Teixeira1, W E Benckhuijsen, P E de Koning, A R P M Valentijn, J W Drijfhout.   

Abstract

We have synthesized a random group of peptides and performed cleavages using various cleavage cocktails including 3,6-dioxa-1,8-octanedithiol (DODT). Purity of the peptides was compared to that obtained with standard protocols for cleavage using RP-HPLC and Maldi-Tof mass spectrometry. We show that stinking thiols can be replaced by the almost odourless (DODT) without negatively affecting the purity of the end product.

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Year:  2002        PMID： 12370025     DOI： 10.2174/0929866023408481

Source DB:  PubMed          Journal:  Protein Pept Lett        ISSN： 0929-8665            Impact factor:   1.890


  11 in total

1.  Structural dynamics and topology of phosphorylated phospholamban homopentamer reveal its role in the regulation of calcium transport.

Authors:  Vitaly V Vostrikov; Kaustubh R Mote; Raffaello Verardi; Gianluigi Veglia
Journal:  Structure       Date:  2013-10-24       Impact factor: 5.006

2.  T-cell recognition of the HspX protein of Mycobacterium tuberculosis correlates with latent M. tuberculosis infection but not with M. bovis BCG vaccination.

Authors:  Annemieke Geluk; May Young Lin; Krista E van Meijgaarden; Eliane M S Leyten; Kees L M C Franken; Tom H M Ottenhoff; Michèl R Klein
Journal:  Infect Immun       Date:  2007-03-26       Impact factor: 3.441

3.  Fmoc Solid Phase Peptide Synthesis of Oxytocin and Analogues.

Authors:  Thomas Kremsmayr; Markus Muttenthaler
Journal:  Methods Mol Biol       Date:  2022

4.  Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity.

Authors:  Simone A Joosten; Krista E van Meijgaarden; Pascale C van Weeren; Fatima Kazi; Annemieke Geluk; Nigel D L Savage; Jan W Drijfhout; Darren R Flower; Willem A Hanekom; Michèl R Klein; Tom H M Ottenhoff
Journal:  PLoS Pathog       Date:  2010-02-26       Impact factor: 6.823

5.  Development of peptide-based lineage-specific serology for chronic Chagas disease: geographical and clinical distribution of epitope recognition.

Authors:  Tapan Bhattacharyya; Andrew K Falconar; Alejandro O Luquetti; Jaime A Costales; Mario J Grijalva; Michael D Lewis; Louisa A Messenger; Trang T Tran; Juan-David Ramirez; Felipe Guhl; Hernan J Carrasco; Patricio Diosque; Lineth Garcia; Sergey V Litvinov; Michael A Miles
Journal:  PLoS Negl Trop Dis       Date:  2014-05-22

6.  Spontaneous head-to-tail cyclization of unprotected linear peptides with the KAHA ligation.

Authors:  Florian Rohrbacher; Gildas Deniau; Anatol Luther; Jeffrey W Bode
Journal:  Chem Sci       Date:  2015-06-10       Impact factor: 9.825

7.  Synthesis, conformation, and activity of human insulin-like peptide 5 (INSL5).

Authors:  Mohammed Akhter Hossain; Ross A D Bathgate; Chze K Kong; Fazel Shabanpoor; Suode Zhang; Linda M Haugaard-Jönsson; K Johan Rosengren; Geoffrey W Tregear; John D Wade
Journal:  Chembiochem       Date:  2008-07-21       Impact factor: 3.164

8.  Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses.

Authors:  Anusha Nathan; Elizabeth J Rossin; Clarety Kaseke; Ryan J Park; Ashok Khatri; Dylan Koundakjian; Jonathan M Urbach; Nishant K Singh; Arman Bashirova; Rhoda Tano-Menka; Fernando Senjobe; Michael T Waring; Alicja Piechocka-Trocha; Wilfredo F Garcia-Beltran; A John Iafrate; Vivek Naranbhai; Mary Carrington; Bruce D Walker; Gaurav D Gaiha
Journal:  Cell       Date:  2021-06-30       Impact factor: 66.850

9.  HLA class-I-peptide stability mediates CD8+ T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV.

Authors:  Clarety Kaseke; Ryan J Park; Nishant K Singh; Dylan Koundakjian; Arman Bashirova; Wilfredo F Garcia Beltran; Overbeck C Takou Mbah; Jiaqi Ma; Fernando Senjobe; Jonathan M Urbach; Anusha Nathan; Elizabeth J Rossin; Rhoda Tano-Menka; Ashok Khatri; Alicja Piechocka-Trocha; Michael T Waring; Michael E Birnbaum; Brian M Baker; Mary Carrington; Bruce D Walker; Gaurav D Gaiha
Journal:  Cell Rep       Date:  2021-07-13       Impact factor: 9.423

10.  Analysis of Mycobacterium tuberculosis-specific CD8 T-cells in patients with active tuberculosis and in individuals with latent infection.

Authors:  Nadia Caccamo; Giuliana Guggino; Serena Meraviglia; Giuseppe Gelsomino; Paola Di Carlo; Lucina Titone; Marialuisa Bocchino; Domenico Galati; Alessandro Matarese; Jan Nouta; Michel R Klein; Alfredo Salerno; Alessandro Sanduzzi; Francesco Dieli; Tom H M Ottenhoff
Journal:  PLoS One       Date:  2009-05-13       Impact factor: 3.240
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