Literature DB >> 12369262

The role of forced swim test on neutrophil leukocytosis observed during inflammation induced by LPS in rodents.

Sonia P Altenburg1, Diana G Ventura, Vilma A Da-Silva, Luciana R Malheiros, Hugo C Castro-Faria-Neto, Patrícia T Bozza, Nancy A Teixeira.   

Abstract

Adult male rats were administered intrapleural (ipl) or intraperitoneal (i.p.) injection of lipopolysaccharide (LPS), 24 h after being submitted to forced swim test (FST). Four hours after LPS challenge, an increase in pleural and peritoneal leukocyte and neutrophil counts in animals not exposed to FST was noted. FST induced a marked increase in pleural, but not in peritoneal, neutrophil leukocytosis. The results suggest that lowered mood may increase inflammatory response to LPS.

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Year:  2002        PMID: 12369262     DOI: 10.1016/s0278-5846(01)00335-9

Source DB:  PubMed          Journal:  Prog Neuropsychopharmacol Biol Psychiatry        ISSN: 0278-5846            Impact factor:   5.067


  1 in total

1.  No fever and leucocytosis in response to a lipopolysaccharide challenge in an insectivorous bat.

Authors:  Sebastian Stockmaier; Dina K N Dechmann; Rachel A Page; M Teague O'Mara
Journal:  Biol Lett       Date:  2015-09       Impact factor: 3.703

  1 in total

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