Fred H Linthicum1. 1. Temporal Bone Laboratory, the House Ear Institute, Los Angeles, California, USA. flinthicum@hei.org
Abstract
OBJECTIVES: To demonstrate the histopathological fate of tissues used for mastoid obliteration over a period of 30 years. STUDY DESIGN: Retrospective histopathological analysis of archival temporal bone microscopic sections. METHODS: From the database of the laboratory, the 17 temporal bones from subjects who had undergone mastoid obliteration procedures were identified. The microscopic appearance of the obliteration tissue was described, and microphotographs made of significant findings. RESULTS: Fat and bone chips, or paté, retained their bulk in the obliterated space, whereas subcutaneous tissue and muscle lost bulk but seemed to promote healing. Some substances, such as bone wax, used for hemostasis and buried under obliteration tissue, were found to produce a subclinical inflammatory reaction, but other materials, such as Surgicel and Gelfoam, did not. CONCLUSIONS: Fat and bone chips, or paté, used as mastoid obliteration tissue, retained their bulk and identity, whereas subcutaneous tissue and muscle did not.
OBJECTIVES: To demonstrate the histopathological fate of tissues used for mastoid obliteration over a period of 30 years. STUDY DESIGN: Retrospective histopathological analysis of archival temporal bone microscopic sections. METHODS: From the database of the laboratory, the 17 temporal bones from subjects who had undergone mastoid obliteration procedures were identified. The microscopic appearance of the obliteration tissue was described, and microphotographs made of significant findings. RESULTS: Fat and bone chips, or paté, retained their bulk in the obliterated space, whereas subcutaneous tissue and muscle lost bulk but seemed to promote healing. Some substances, such as bone wax, used for hemostasis and buried under obliteration tissue, were found to produce a subclinical inflammatory reaction, but other materials, such as Surgicel and Gelfoam, did not. CONCLUSIONS: Fat and bone chips, or paté, used as mastoid obliteration tissue, retained their bulk and identity, whereas subcutaneous tissue and muscle did not.
Authors: Bo Gyung Kim; Hyo Jun Kim; Seung Jae Lee; Eunsang Lee; Se A Lee; Jong Dae Lee Journal: Clin Exp Otorhinolaryngol Date: 2019-02-01 Impact factor: 3.372