| Literature DB >> 1236773 |
Abstract
Oestradiol injection on Day 10 of pregnancy in rats, resulted in either ovulation or luteinization in 50% of cases on Day 12. Cytological data showed that the number of pituitary LH cells decreased significantly on Day 11 in all oestradiol-treated animals whether responsive or not to oestrogen by ovarian modifications, while the number of pituitary FSH cells only decreased significantly in females with characteristic ovarian signs of preovulation. Bioassay of pituitary FSH confirmed the cytological data. It is concluded that ovulation and luteinization only occurred in the pregnant rat when oestradiol triggered off a synchronous release of LH and FSH.Entities:
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Year: 1975 PMID: 1236773 DOI: 10.1007/bf00220001
Source DB: PubMed Journal: Cell Tissue Res ISSN: 0302-766X Impact factor: 5.249