| Literature DB >> 12366791 |
U Shankarkumar1, K Ghosh, D Mohanty.
Abstract
We have characterized HLA B27 alleles in a sample population of Maharastra, Western Indians (n = 51), with the aim to investigate the different subtypes present among this population. The study was carried out using polymerase chain reaction with sequence-specific primers (PCR-SSP) and reverse line strip (RLS) techniques. Significant new findings have arisen from this study: B*2704, B*2705, B*2707, B*2708 and B*2714 alleles were found to be present, and two novel B27 alleles, B*2708 and B*2714, were found in this Indian population. In addition, B*2714 was observed in a patient with ankylosing spondylitis. This association has not been previously reported in ethnic groups from India.Entities:
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Year: 2002 PMID： 12366791 DOI： 10.1034/j.1399-0039.2002.600115.x
Source DB: PubMed Journal: Tissue Antigens ISSN： 0001-2815