BACKGROUND: After surgical removal, anal canal condyloma (ACC) has a higher risk of recurrence compared with extragenital warts. OBJECTIVES: To reduce local recurrences of ACC using follow-up treatment with imiquimod-containing suppositories (anal tampons). METHODS: After ablation of ACC, 10 male patients received treatment with imiquimod suppositories three times weekly for 3-4 months. RESULTS: Treatment with imiquimod anal tampons was well tolerated. Early initial recurrences in some patients cleared after treatment with the imiquimod suppositories. Within a mean follow-up of 9 months no patient demonstrated recurrence of ACC. CONCLUSIONS: These data suggest that imiquimod anal tampons may represent a new therapeutic option to prevent recurrences of ACC following ablative surgery.
BACKGROUND: After surgical removal, anal canal condyloma (ACC) has a higher risk of recurrence compared with extragenital warts. OBJECTIVES: To reduce local recurrences of ACC using follow-up treatment with imiquimod-containing suppositories (anal tampons). METHODS: After ablation of ACC, 10 male patients received treatment with imiquimod suppositories three times weekly for 3-4 months. RESULTS: Treatment with imiquimod anal tampons was well tolerated. Early initial recurrences in some patients cleared after treatment with the imiquimod suppositories. Within a mean follow-up of 9 months no patient demonstrated recurrence of ACC. CONCLUSIONS: These data suggest that imiquimod anal tampons may represent a new therapeutic option to prevent recurrences of ACC following ablative surgery.
Authors: Felix Aigner; Friedrich Conrad; Andreas Widschwendter; Robert Zangerle; Bettina Zelger; Alfred Haidenberger; Sebastian Roka; Kurt Heim; Reinhard Höpfl; Martin Klimpfinger; Yves Marcus Rigler; Hugo Bonatti; Johann Pfeifer; Andrea Maier; Reinhard Kirnbauer; Andreas Salat Journal: Wien Klin Wochenschr Date: 2008 Impact factor: 1.704
Authors: G A Binda; G Gagliardi; I Dal Conte; M Verra; P Cassoni; E Cavazzoni; E Stocco; S Delmonte; P De Nardi; L Sticchi; M Mistrangelo Journal: Tech Coloproctol Date: 2019-06-26 Impact factor: 3.781