| Literature DB >> 12364961 |
Cláudio Esteves Tatsui1, Andrei Koerbel, Daniel Monte-Serrat Prevedello, João Candido Araújo, Léo Fernando Silva Ditzel, Luis Fernando Bleggi-Torres.
Abstract
Granulocytic sarcoma is a solid tumor, composed by granulocytic precursor cells at various levels of differentiation, located at an extra-medullary site. It is associated with acute myeloid leukemia, and its presence reveals a bad prognostic factor. The treatment usually consists of radiotherapy and chemotherapy. A case of an intracranial granulocytic sarcoma occurring six months after a bone marrow transplant in a patient with acute myeloid leukemia is reported. The patient presented with headache and left hemiplegia caused by a large fronto-parietal lesion with significant mass effect. After a complete surgical resection there was a full recovery of the deficit. The patient completed radiotherapy and chemotherapy with no evidence of disease after three months of follow-up. Surgery is indicated in the presence of progressive neurological deficit. Surgical decompression may provide rapid improvement and therefore, affect quality of survival.Entities:
Mesh:
Year: 2002 PMID: 12364961
Source DB: PubMed Journal: Arq Neuropsiquiatr ISSN: 0004-282X Impact factor: 1.420