Literature DB >> 12364961

[Central nervous system granulocytic sarcoma after bone marrow transplant: case report].

Cláudio Esteves Tatsui1, Andrei Koerbel, Daniel Monte-Serrat Prevedello, João Candido Araújo, Léo Fernando Silva Ditzel, Luis Fernando Bleggi-Torres.   

Abstract

Granulocytic sarcoma is a solid tumor, composed by granulocytic precursor cells at various levels of differentiation, located at an extra-medullary site. It is associated with acute myeloid leukemia, and its presence reveals a bad prognostic factor. The treatment usually consists of radiotherapy and chemotherapy. A case of an intracranial granulocytic sarcoma occurring six months after a bone marrow transplant in a patient with acute myeloid leukemia is reported. The patient presented with headache and left hemiplegia caused by a large fronto-parietal lesion with significant mass effect. After a complete surgical resection there was a full recovery of the deficit. The patient completed radiotherapy and chemotherapy with no evidence of disease after three months of follow-up. Surgery is indicated in the presence of progressive neurological deficit. Surgical decompression may provide rapid improvement and therefore, affect quality of survival.

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Year:  2002        PMID: 12364961

Source DB:  PubMed          Journal:  Arq Neuropsiquiatr        ISSN: 0004-282X            Impact factor:   1.420


  1 in total

1.  Multiple intracranial tuberculomas mimicking granulocytic sarcomas in acute myeloid leukemia.

Authors:  Jae Sook Ahn; Duk Hwan Yang; Yoe Kyeoung Kim; Sang Hee Cho; In Young Kim; Je Jung Lee; Ik Joo Chung; Hyeoung Joon Kim
Journal:  J Korean Med Sci       Date:  2007-09       Impact factor: 2.153

  1 in total

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