Literature DB >> 12361591

Dual role of Ang2 in postnatal angiogenesis and lymphangiogenesis.

Tanja Veikkola1, Kari Alitalo.   

Abstract

The maturation of the vascular system and the adjustment of blood vessel density in tissues require the opposing processes of vessel growth and regression. A new study in this issue of Developmental Cell shows that Angiopoietin-2 (Ang2), a ligand for the endothelial Tie2 receptor tyrosine kinase, has a dual function in the processes of postnatal angiogenesis and vascular remodeling. Also, Ang2 signals are required for the proper development and function of the lymphatic vessels.

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Year:  2002        PMID： 12361591     DOI： 10.1016/s1534-5807(02)00231-9

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


  10 in total

1.  Hepatocyte growth factor mediates angiopoietin-induced smooth muscle cell recruitment.

Authors:  Hanako Kobayashi; Laura M DeBusk; Yael O Babichev; Daniel J Dumont; Pengnian Charles Lin
Journal:  Blood       Date:  2006-04-25       Impact factor: 22.113

2.  Model of vascular desmoplastic multispecies tumor growth.

Authors:  Chin F Ng; Hermann B Frieboes
Journal:  J Theor Biol       Date:  2017-05-18       Impact factor: 2.691

3.  b-FGF induces corneal blood and lymphatic vessel growth in a spatially distinct pattern.

Authors:  Amir R Hajrasouliha; Zahra Sadrai; Sunil K Chauhan; Reza Dana
Journal:  Cornea       Date:  2012-07       Impact factor: 2.651

4.  Angiopoietin-2 in experimental colitis.

Authors:  Vijay C Ganta; Walter Cromer; Ginny L Mills; James Traylor; Merilyn Jennings; Sarah Daley; Benjamin Clark; J Michael Mathis; Michael Bernas; Moheb Boktor; Paul Jordan; Marlys Witte; J Steven Alexander
Journal:  Inflamm Bowel Dis       Date:  2010-06       Impact factor: 5.325

Review 5.  Using gene expression profiling to identify the molecular basis of the synergistic actions of hepatocyte growth factor and vascular endothelial growth factor in human endothelial cells.

Authors:  Mary E Gerritsen; James E Tomlinson; Constance Zlot; Michael Ziman; Stuart Hwang
Journal:  Br J Pharmacol       Date:  2003-09-22       Impact factor: 8.739

6.  Collaborative interplay between FGF-2 and VEGF-C promotes lymphangiogenesis and metastasis.

Authors:  Renhai Cao; Hong Ji; Ninghan Feng; Yin Zhang; Xiaojuan Yang; Patrik Andersson; Yuping Sun; Katerina Tritsaris; Anker Jon Hansen; Steen Dissing; Yihai Cao
Journal:  Proc Natl Acad Sci U S A       Date:  2012-09-11       Impact factor: 11.205

Review 7.  Understanding lymphangiogenesis in knockout models, the cornea, and ocular diseases for the development of therapeutic interventions.

Authors:  Jessica F Yang; Amit Walia; Yu-hui Huang; Kyu-yeon Han; Mark I Rosenblatt; Dimitri T Azar; Jin-Hong Chang
Journal:  Surv Ophthalmol       Date:  2015-12-17       Impact factor: 6.048

8.  Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivo.

Authors:  Meit Björndahl; Renhai Cao; L Johan Nissen; Steve Clasper; Louise A Johnson; Yuan Xue; Zhongjun Zhou; David Jackson; Anker Jon Hansen; Yihai Cao
Journal:  Proc Natl Acad Sci U S A       Date:  2005-10-17       Impact factor: 11.205

9.  Hypoxia and extracellular matrix proteins influence angiogenesis and lymphangiogenesis in mouse embryoid bodies.

Authors:  Andrea M Foskett; Uthayashanker R Ezekiel; Jerome P Trzeciakowski; David C Zawieja; Mariappan Muthuchamy
Journal:  Front Physiol       Date:  2011-12-20       Impact factor: 4.566

10.  Emerging Role of Sphingosine-1-phosphate in Inflammation, Cancer, and Lymphangiogenesis.

Authors:  Wei-Ching Huang; Masayuki Nagahashi; Krista P Terracina; Kazuaki Takabe
Journal:  Biomolecules       Date:  2013
  10 in total

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