Literature DB >> 12361325

Adsorption of radioiodine on platinum: a fast and simple column method to obtain concentrated and pure radioiodide in either water or anhydrous solvents.

A H Brake1, F P Moet, R E van der Zwart, J L H Eersels, J D M Herscheid.   

Abstract

Radioiodine can be adsorbed on a small column filled with platinum powder from an acidified aqueous solution. The adsorption is nearly quantitative, irrespective of the oxidation state of the iodine used. With an alternated flow of hydrogen gas and solvent, the iodine can be desorbed from the platinum into an aqueous or organic solvent. Depending on the solvent used, the desorption process is also nearly quantitative, and the eluate obtained contains almost pure radioiodide. Using this method, labelling reactions with radioiodide are no longer restricted to water-stable substrates and catalysts.

Entities:  

Year:  2002        PMID: 12361325     DOI: 10.1016/s0969-8043(02)00133-1

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  1 in total

1.  High-quality 124I-labelled monoclonal antibodies for use as PET scouting agents prior to 131I-radioimmunotherapy.

Authors:  Iris Verel; Gerard W M Visser; Maria J W D Vosjan; Ronald Finn; Ronald Boellaard; Guus A M S van Dongen
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-07-31       Impact factor: 9.236

  1 in total

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