Literature DB >> 12360276

Clinical translation of angiogenesis inhibitors.

Robert Kerbel1, Judah Folkman.   

Abstract

Angiogenesis inhibitors are a new class of drugs, for which the general rules involving conventional chemotherapy might not apply. The successful translation of angiogenesis inhibitors to clinical application depends partly on the transfer of expertise from scientists who are familiar with the biology of angiogenesis to clinicians. What are the most common questions that clinicians ask as they begin to test angiogenesis inhibitors in cancer clinical trials?

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Year:  2002        PMID: 12360276     DOI: 10.1038/nrc905

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN: 1474-175X            Impact factor:   60.716


  314 in total

Review 1.  Adding to the mix: fibroblast growth factor and platelet-derived growth factor receptor pathways as targets in non-small cell lung cancer.

Authors:  S A Kono; L E Heasley; R C Doebele; D R Camidge
Journal:  Curr Cancer Drug Targets       Date:  2012-02       Impact factor: 3.428

2.  Activation of iCaspase-9 in neovessels inhibits oral tumor progression.

Authors:  M S Pinsky; W Song; Z Dong; K Warner; B Zeitlin; E Karl; D E Hall; J E Nör
Journal:  J Dent Res       Date:  2006-05       Impact factor: 6.116

3.  Early genetic mechanisms underlying the inhibitory effects of endostatin and fumagillin on human endothelial cells.

Authors:  Chiara M Mazzanti; Anita Tandle; Dominique Lorang; Nick Costouros; David Roberts; Generoso Bevilacqua; Steven K Libutti
Journal:  Genome Res       Date:  2004-08       Impact factor: 9.043

4.  Vasohibin: the feedback on a new inhibitor of angiogenesis.

Authors:  Robert S Kerbel
Journal:  J Clin Invest       Date:  2004-10       Impact factor: 14.808

5.  Dynamic contrast enhanced ultrasound assessment of the vascular effects of novel therapeutics in early stage trials.

Authors:  Edward Leen; Michalakis Averkiou; Marcel Arditi; Peter Burns; Daniela Bokor; Thomas Gauthier; Yuko Kono; Olivier Lucidarme
Journal:  Eur Radiol       Date:  2012-07       Impact factor: 5.315

6.  Endostatin and angiostatin are increased in diabetic patients with coronary artery disease and associated with impaired coronary collateral formation.

Authors:  Neel R Sodha; Richard T Clements; Munir Boodhwani; Shu-Hua Xu; Roger J Laham; Cesario Bianchi; Frank W Sellke
Journal:  Am J Physiol Heart Circ Physiol       Date:  2008-12-12       Impact factor: 4.733

7.  Genetic loci that control the size of laser-induced choroidal neovascularization.

Authors:  Kei Nakai; Michael S Rogers; Takashi Baba; Taisaku Funakoshi; Amy E Birsner; Dema S Luyindula; Robert J D'Amato
Journal:  FASEB J       Date:  2009-02-23       Impact factor: 5.191

8.  The transcription factor Net regulates the angiogenic switch.

Authors:  Hong Zheng; Christine Wasylyk; Abdelkader Ayadi; Joseph Abecassis; Jack A Schalken; Hermann Rogatsch; Nicolas Wernert; Sauveur-Michel Maira; Marie-Christine Multon; Bohdan Wasylyk
Journal:  Genes Dev       Date:  2003-09-15       Impact factor: 11.361

9.  RNA interference-mediated gene silencing of vascular endothelial growth factor in colon cancer cells.

Authors:  Tie-Jun Li; Jian-Ning Song; Kai Kang; Shu-Sheng Tong; Zan-Lan Hu; Tong-Chuan He; Bing-Qiang Zhang; Cai-Quan Zhang
Journal:  World J Gastroenterol       Date:  2007-10-28       Impact factor: 5.742

10.  Induction of Vasculogenic Mimicry Overrides VEGF-A Silencing and Enriches Stem-like Cancer Cells in Melanoma.

Authors:  Caroline I Schnegg; Moon Hee Yang; Subrata K Ghosh; Mei-Yu Hsu
Journal:  Cancer Res       Date:  2015-03-13       Impact factor: 12.701

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