| Literature DB >> 12359826 |
Georgia B Vogelsang1, Linda Lee, Debra M Bensen-Kennedy.
Abstract
Stem cell transplantation is being used to treat a number of hematologic malignancies as well as hematologic and immune deficiency states. The ages of patients being offered this therapy and the donor marrow sources have been expanded. One persistent problem has been graft-versus-host disease (GVHD). This article reviews the basic biology of GVHD, clinical manifestations of acute and chronic GVHD, prophylaxis and treatment of acute GVHD, and treatment of chronic GVHD.Entities:
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Year: 2001 PMID: 12359826 DOI: 10.1146/annurev.med.54.101601.152339
Source DB: PubMed Journal: Annu Rev Med ISSN: 0066-4219 Impact factor: 13.739