Literature DB >> 12358828

Multiple synchronous cutaneous melanomas: implications for prevention.

Paolo Carli1, Vincenzo De Giorgi, Alessandra Chiarugi, Marcello Stante, Benvenuto Giannotti.   

Abstract

BACKGROUND: A subset of about 3-5% of melanoma patients present a second primary melanoma. OBSERVATIONS: We describe two cases of primary multiple synchronous melanomas consecutively observed in the last 6 months in our department in two male patients presenting multiple atypical nevi. In both patients, the second melanoma was diagnosed by the clinician who had identified the first one, but at the time of the first follow-up consultation, 3 months later. The delayed discovery of the second melanoma required another referral for surgery with additional discomfort for the patients. Concern about the first lesion (the thickest in both cases) probably rendered the second one less evident to both patients and clinician, until the first follow-up examination after excision of the first lesion.
CONCLUSION: We stress the need for careful and thorough examination of the whole body surface at the time of detection of a cutaneous melanoma in subjects with multiple atypical moles because the finding of synchronous multiple melanomas is not uncommon.

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Mesh:

Year:  2002        PMID: 12358828     DOI: 10.1046/j.1365-4362.2002.01605.x

Source DB:  PubMed          Journal:  Int J Dermatol        ISSN: 0011-9059            Impact factor:   2.736


  6 in total

1.  Risk Factors of Subsequent Primary Melanomas in Austria.

Authors:  Christoph Müller; Judith Wendt; Sabine Rauscher; Raute Sunder-Plassmann; Erika Richtig; Ingrid Fae; Gottfried Fischer; Ichiro Okamoto
Journal:  JAMA Dermatol       Date:  2019-02-01       Impact factor: 10.282

Review 2.  Epidemiological and genetic factors underlying melanoma development in Italy.

Authors:  Giuseppe Palmieri; Maria Colombino; Milena Casula; Mario Budroni; Antonella Manca; Maria Cristina Sini; Amelia Lissia; Ignazio Stanganelli; Paolo A Ascierto; Antonio Cossu
Journal:  Melanoma Manag       Date:  2015-05-18

3.  Clinicopathologic features of incident and subsequent tumors in patients with multiple primary cutaneous melanomas.

Authors:  Rajmohan Murali; Chris Goumas; Anne Kricker; Lynn From; Klaus J Busam; Colin B Begg; Terence Dwyer; Stephen B Gruber; Peter A Kanetsky; Irene Orlow; Stefano Rosso; Nancy E Thomas; Marianne Berwick; Richard A Scolyer; Bruce K Armstrong
Journal:  Ann Surg Oncol       Date:  2011-09-13       Impact factor: 5.344

4.  Activating PIK3CA mutations coexist with BRAF or NRAS mutations in a limited fraction of melanomas.

Authors:  Antonella Manca; Amelia Lissia; Mariaelena Capone; Paolo A Ascierto; Gerardo Botti; Corrado Caracò; Ignazio Stanganelli; Maria Colombino; MariaCristina Sini; Antonio Cossu; Giuseppe Palmieri
Journal:  J Transl Med       Date:  2015-01-28       Impact factor: 5.531

5.  Barriers and facilitators of adherence to medical advice on skin self-examination during melanoma follow-up care.

Authors:  Annett Körner; Martin Drapeau; Brett D Thombs; Zeev Rosberger; Beatrice Wang; Manish Khanna; Alan Spatz; Adina Coroiu; Rosalind Garland; Gerald Batist
Journal:  BMC Dermatol       Date:  2013-03-01

6.  Discrepant alterations in main candidate genes among multiple primary melanomas.

Authors:  Maria Colombino; MariaCristina Sini; Amelia Lissia; Vincenzo De Giorgi; Ignazio Stanganelli; Fabrizio Ayala; Daniela Massi; Corrado Rubino; Antonella Manca; Panagiotis Paliogiannis; Susanna Rossari; Serena Magi; Laura Mazzoni; Gerardo Botti; Mariaelena Capone; Marco Palla; Paolo A Ascierto; Antonio Cossu; Giuseppe Palmieri
Journal:  J Transl Med       Date:  2014-05-08       Impact factor: 5.531

  6 in total

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