Literature DB >> 12357812

Rapid hydrolytic cleavage of the mRNA model compound HPNP by glycine based macrocyclic lanthanide ribonuclease mimics.

Thorfinnur Gunnlaugsson1, R Jeremy H Davies, Mark Nieuwenhuyzen, Clarke S Stevenson, Romain Viguier, Sinead Mulready.   

Abstract

The lanthanide ion based macrocyclic complexes 1.Ln mimic the hydrophobic nature of ribonucleases, where the lanthanide ions induce the formation of a hydrophobic cavity for 1, giving rise to a large order of magnitude enhancement in the hydrolytic cleavage of HPNP.

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Year:  2002        PMID: 12357812     DOI: 10.1039/b205349g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Fabrication of highly active phosphatase-like fluorescent cerium-doped carbon dots for in situ monitoring the hydrolysis of phosphate diesters.

Authors:  Jinyan Du; Shuangqing Qi; Juan Chen; Ying Yang; Tingting Fan; Ping Zhang; Shujuan Zhuo; Changqing Zhu
Journal:  RSC Adv       Date:  2020-11-14       Impact factor: 4.036

  1 in total

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